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Table 2 Changes of vessel density (%), FAZ area (mm2), thickness (μm) in macular area in insulin intensive group (n = 36)

From: Effects of intensive insulin therapy on the retinal microvasculature in patients with type 2 diabetes mellitus: a prospective observational study

Macular Parameters

Pre-treatment

After treatment

1 M

3 M

6 M

SCP-VD

49.1 ± 2.8

48.0 ± 3.1

46.6 ± 2.7*

48.4 ± 3.1

DCP-VD

51.9 ± 3.9

47.8 ± 6.4*

45.9 ± 5.9*

46.1 ± 5.5*

FD-300

52.7 ± 4.0

50.3 ± 4.6

49.0 ± 4.7*

50.4 ± 4.2

FAZ area

0.28 ± 0.06

0.30 ± 0.05

0.31 ± 0.06

0.31 ± 0.06

Fovea thickness

251.7 ± 11.3

250.3 ± 11.0

248.4 ± 11.2

249.2 ± 10.9

Macular thickness

283.3 ± 17.4

282.4 ± 16.4

281.4 ± 14.4

282.9 ± 15.6

  1. For the insulin intensive group, the significant changes compared with pre-treatment are marked with asterisks
  2. SCP superficial capillary plexus; DCP deep capillary plexus; FAZ foveal avascular zone; FD-300 foveal density in a 300μm wide region around FAZ; 1M 1 month; 3M 3 months; 6M 6 months