Table 2 Suggested support to minimise discontinuation in a trial of medical presbyopia treatments

▪ Psychological support

▪ Engagement as a true science participant partner and not a ‘study subject'

▪ Support with day-to-day organisation on visit days

▪ Option to ask questions of study investigator/ study nurse

▪ Free or discounted routine check-ups

▪ Simple automatic reminders to keep people on track

▪ Minimal number of interventions and tests to minimise disruption

▪ Availability of FAQs

▪ Phone line/ virtual support community with knowledgeable moderator