Retinal ganglion cell layer thickness and volume measured by OCT changes with age, sex, and axial length in a healthy population

Table 2 GCL parameter values stratified by sex and by retinal sector. * P value < 0.05

		Female		Male		All subjects		P value
	Anatomic location	Mean ± SD	Range	Mean ± SD	Range	Mean ± SD	Range	P value
GCL thickness (µm)	GCL C	14.5 ± 3.2	9–25	16.9 ± 3.9	9–25	15.6 ± 3.7	9–25	0.101
	GCL T1	48.7 ± 4.8	36–60	50.4 ± 3.9	42–60	49.5 ± 4.5	36–60	0.387
	GCL S1	53.3 ± 4.2	44–64	55 ± 4	46–62	54 ± 4.2	44–64	0.858
	GCL N1	52 ± 5	42–63	53.7 ± 4.3	45–63	52.7 ± 4.8	42–63	0.314
	GCL I1	52.8 ± 5	35–64	54.8 ± 4.4	44–64	53.7 ± 4.8	35–64	0.822
	GCL T2	36.7 ± 4.1	29–47	38.3 ± 3.2	31–44	37.4 ± 3.8	29–47	0.052
	GCL S2	35 ± 3.2	29–43	35.8 ± 2.6	30–41	35.4 ± 3	29–43	0.135
	GCL N2	38.4 ± 3.7	30–47	38.6 ± 3.2	33–44	38.5 ± 3.5	30–47	0.186
	GCL I2	33.4 ± 3.7	26–42	33.9 ± 2.4	29–39	33.6 ± 3.2	26–42	< 0.001*
	Inner ring	51.7 ± 4.4	42–63	53.4 ± 3.9	45–62	52.5 ± 4.3	42–63	0.521
	Outer ring	35.9 ± 3.4	29.7–43.7	36.7 ± 2.5	32–41.3	36.2 ± 3	29.8–43.8	0.014*
	TT	42.7 ± 4.1	33.5–53.0	44.4 ± 3.2	38.0–52.0	43.4 ± 3.8	33.5–53.0	0.128
	NN	45.2 ± 3.7	39.0–55.0	46.1 ± 3.2	39.5–53.0	45.6 ± 3.5	39.0–55.0	0.254
	SS	44.1 ± 3.4	39.0–53.0	45.4 ± 2.9	38.5–53.0	44.7 ± 3.2	38.5–53.0	0.140
	II	43.1 ± 3.8	33.5–52.0	44.3 ± 3.0	37.0–50.0	43.6 ± 3.5	33.5–52.0	0.175
GCL volume (mm³)		1.09 ± 0.09	0.97–1.33	1.13 ± 0.07	0.99–1.27	1.1 ± 0.08	0.97–1.33	0.009*

N = 51 eyes for males, 65 eyes for females; GCLV = total GCL volume; anatomic locations represent different sectors according to Fig. 2; SD Standard deviation

ISSN: 1471-2415