Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia

BMC Ophthalmology

Table 1 Comparison of the retinal nerve fiber layer, global asymmetry, macular thickness map, and S-I hemisphere asymmetry between transfusion-dependent β-thalassemia patients and controls

Groups Variables (μm)	Patients (n=39)	Controls (n=27)	P-value
Groups Variables (μm)	Mean ± SD	Mean ± SD	P-value
Global (Average) RNFL	101.87 ±11.02	99.22 ±9.95	0.322
Superior RNFL	122.38 ± 24.01	120.51±14.56	0.720
Inferior RNFL	137.84 ± 20.94	131.29 ± 18.56	0.196
Temporal RNFL	72.35 ± 12.64	70.88 ± 9.20	0.607
Nasal RNFL	74.94 ± 15.55	74.11 ± 12.59	0.817
Global RNFL asymmetry	-0.487 ± 4.91 Median, range : 0, -18 -9	-1.07 ± 5.62 Median, range: -1, -14 -15	0.420
Macular thickness map	293.59 ± 13.55	293.68 ± 11.31	0.980
S-I hemisphere asymmetry^a	6.10 ± 13.07 Median, range: 3, 0-68	3.75 ± 3.29 Median, range: 2, 0-9	0.483

The Student t-test was used for all comparisons between the two groups, except for global RNFL asymmetry and S-I asymmetry which Mann-Whitney test was used
SD Standard deviation, RNFL Retinal nerve fiber layer
^aThe absolute difference of average macular thickness between superior and inferior hemisphere

ISSN: 1471-2415