Table 5 Correlation of the retinal nerve fiber layer, global asymmetry, macular thickness map, and S-I hemisphere asymmetry measurements with hemoglobin and serum ferritin levels, age, and type of iron chelation therapy of the patients with transfusion-dependent β-thalassemia patients
From: Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia
(μm) | Hemoglobin (g/dl) | Ferritin (ng/ml) | Age (year) | Iron Chelation Therapy | |||||
|---|---|---|---|---|---|---|---|---|---|
Correlation coefficient | P-value | Correlation coefficient | P-value | Correlation coefficient | P-value | Mono therapy n=17 mean±SD | Combined therapy n=22 mean±SD | P value | |
Global (average) RNFL | -0.096 | 0.563 | -0.267 | 0.100 | -0.082 | 0.621 | 104±9 | 100±12 | 0.269 |
Superior RNFL | -0.107 | 0.516 | -0.328 | 0.042 | -0.090 | 0.584 | 125±16 | 120±28 | 0.539 |
Inferior RNFL | 0.068 | 0.679 | -0.192 | 0.241 | 0.048 | 0.774 | 141±16 | 135±24 | 0.407 |
Temporal RNFL | -0.235 | 0.150 | 0 | >0.999 | 0.015 | 0.927 | 74±15 | 70±10 | 0.327 |
Nasal RNFL | -0.024 | 0.886 | -0.005 | 0.974 | -0.195 | 0.233 | 75±16 | 74±15 | 0.793 |
Global RNFL asymmetry | -0.084 | 0.610 | -0.163 | 0.320 | 0.008 | 0.962 | 2(-10-9) median range | -0.5 (-18-5) median range | 0.566 |
Macular thickness map | -0.182 | 0.267 | -0.254 | 0.118 | -0.218 | 0.183 | 293±11 | 293±15 | 0.851 |
S-I hemisphere aymmetrya | 0.165 | 0.315 | -0.064 | 0.697 | 0.262 | 0.107 | 3 (0-10) median range | 2.5 (0-68) median range | 0.624 |