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Table 2 Serum and tear PAI-1 and tPA levels among subjects with Type 2 Diabetes with or without retinopathy

From: Relationship between serum and tear levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in diabetic retinopathy

Parameters

Median (IQR)

P value*

DR

No DR

PAI-1 level in tears (ng/ml),

0.24 (0.06)

0.22 (0.03)

0.122

PAI-1 level in blood (ng/ml),

32.72 (32.52)

21.37 (14.93)

0.025**

tPA level in tears (ng/ml)

0.46 (0.02)

0.46 (0.12)

0.582

tPA level in blood (ng/ml)

3.48 (5.06)

3.94 (6.72)

0.090

  1. Data are presented as median (interquartile range). PAI-1 Plasminogen activator inhibitor-1, tPA tissue plasminogen activator
  2. **P value < 0.05 (Mann–Whitney test)