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Table 3 Univariate analysis demonstrating correlation of serum and tear PAI-1 levels with other variables in patients with DR

From: Relationship between serum and tear levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in diabetic retinopathy

Parameters

PAI-1 tears

PAI-1 blood

tPA tears

tPA blood

ra (p value)b

r (p value)

r (p value)

r (p value)

BMI

0.555 (0.026)*

0.194 (0.388)

-0.271 (0.449)

0.427 (0.060)

Age

-0.099 (0.715)

0.230 (0.304)

-0.105 (0.774)

0.024 (0.920)

DM duration

-0.010 (0.972)

0.183 (0.416)

0.031 (0.933)

0.175 (0.459)

HbA1c

0.377 (0.150)

-0.219 (0.327)

0.240 (0.504)

-0.005 (0.982)

FBS

0.120 (0.659)

-0.267 (0.229)

0.412 (0.236)

-0.009 (0.970)

CRP

0.289 (0.278)

0.281 (0.205)

0.086 (0.813)

0.255 (0.278)

Uric acid

0.325 (0.219)

-0.119 (0.597)

-0.394 (0.260)

0.146 (0.539)

UACR

-0.075 (0.782)

0.056 (0.085)

0.080 (0.826)

-0.107 (0.654)

  1. aSpearman correlation test
  2. bP value < 0.05
  3. *correlation is significant at the 0.05 level
  4. BMI Body mass index, HbA1c Hemoglobin A1c, DM Diabetes mellitus, FBS Fasting blood sugar, CRP C-reactive protein, UACR Urinary albumin-to-creatinine ratio