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Table 3 Comparison of visual outcomes between different ethnic groups

From: Ethnic differences on long term outcomes of polypoidal choroidal vasculopathy after predominantly bevacizumab monotherapy

 

12 months

36 months

36 months (Caucasian)

36 months (Non-Caucasian)

p-value

No. of eyes

89

89

48

41

–

Mean ± SD final VA, letters

67.0 ± 16.4

63.2 ± 21.0

70.5 ± 12.0

54.7 ± 25.8

< 0.001b

Mean ± SD CRT, microns

307.3 ± 146.5

295.4 ± 122.2

269.9 ± 77.0

327.0 ± 157.2

0.269b

Mean change in VA letters (95% CI)

+ 8.9 (2.7 to 10.5)

+ 5.0 (− 2.7 to 8.8)

+ 7.6 (3.2 to 12.0)

+ 2.0 (− 5.8 to 9.8)

0.581b

Proportion with ≥15-letter gain

24 (27.0%)

29 (32.6%)

17 (35.4%)

12 (29.3%)

0.651c

Proportion with ≤15-letter loss

84 (94.4%)

78 (87.6%)

44 (91.7%)

34 (82.9%)

0.333c

VA ≥70 letters (20/40 Snellen equivalent)

48 (53.9%)

47 (52.8%)

33 (68.8%)

14 (34.1%)

0.001c

Mean total ± SD, no. of injections

5.8 ± 2.9

13.8 ± 8.1

14.0 ± 8.1

13.6 ± 8.1

0.833d

Received PDT, no. (%)

5 (5.6%)

14 (15.7%)

4 (8.3%)

10 (24.4%)

0.08c

Mean time to PDT (SD), months

–

–

30 (15.2)

19.1 (15.6)

0.185d

Polyp regression, no (%)a

2/24 (8.3%)-

12/24 (50.0%)

7/10 (70.0%)

5/14 (35.7%)

0.214c

Mean time to Polyp Regression (SD), monthsa

–

–

45.3 (33.5)

34 (19.9)

0.519d

Received Aflibercept or Ranibizumab, no. (%)

6 (6.7%)

15 (16.9%)

11 (22.9%)

4 (9.8%)

0.155c

  1. CRT Central Retinal Thickness, VA Visual acuity, CI Confidence interval, SD Standard deviation, PDT Photodynamic therapy
  2. aFindings based on 24 patients that underwent repeat ICGA
  3. bWilcoxon Rank-Sum test
  4. cFisher’s exact test
  5. dStudent t-test