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Table 4 Comparison of ocular surface and MG parameters between the young and elderly Demodex positive patients

From: The correlation between Demodex infestation and meibomian gland dysfunction at different ages

 

Young

Elderly

P value

Mean Demodex counts

7.60 ± 4.71

10.64 ± 7.50

0.014

Sex; male (n)

24

14

0.008^

  female

24

42

 

OSDI

23.11 ± 11.48

25.99 ± 11.13

0.207*

FBUT

4.85 ± 2.04

3.77 ± 1.73

0.005

CFS

0.98 ± 1.60

1.32 ± 1.88

0.182

SIT(mm)

10.66 ± 7.87

8.72 ± 6.23

0.304

LLT(nm)

62.68 ± 23.37

79.76 ± 22.03

0.001*

MG dropout

2.31 ± 1.52

3.35 ± 1.29

0.000

Plugging of MG orifices

4.60 ± 1.21

5.19 ± 1.19

0.006

Lid marginabnormality

3.36 ± 1.03

4.32 ± 1.42

0.000

MG expression

5.06 ± 3.35

7.45 ± 3.57

0.001*

Meibum quality

12.81 ± 5.32

14.89 ± 4.21

0.032*

  1. MG Meibomian gland, OSDI Ocular surface disease index, FBUT Fluorescein tear film break-up time, CFS Corneal fluorescein staining, SIT Schirmer test I, LLT Lipid layer thickness
  2. P-value determined by Mann–Whitney U test; ^ indicates Pearson’sχ2 test, * indicates independent t-test
  3. Significant P-values (P < 0.05) are in bold