Fig. 4
A 75-year-old male in the intravitreal brolucizumab (IVBr) treatment group at base line (A-I). A Fundus photograph showed pigment epithelial detachment (PED) at the macula. B, C Optical coherence tomography (OCT; horizontal (B) and vertical images (C) revealed PED with subretinal fluid. D Fundus autofluorescence image. E, F Early and late phase of fluorescein angiography detected occult macular neovascularization (MNV) at the macula. G, H Early and late phase of indocyanine green angiography identified MNV at the bottom of PED I OCT angiography showed MNV at the bottom of the lesion. OCT images of the case at 1,2 and 3 months after IVBr treatment (J-L). At 1 month after treatment, PED dramatically regressed (J, K). At 2 months, the PED gradually reduced and almost disappeared at 3 months (L)