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Table 2 Characteristics of included studies

From: Observation, laser photocoagulation or anti-VEGF therapy in the management of retinal arterial macroaneurysms

Study

Year

N

Sex (Female, %)

Mean age

Treatment

N

Exudative RAM (%)

Mean Interval (m)

Baseline LogMAR VA (mean VA in decimal)

Baseline CMT (μm)

Palestine

1982

31

22(71)

68.0

Observation

25

18(72)

35.4

0.63 ± 0.71 (0.23)

NA

     

Laser

6

6(100)

36.1

0.48 ± 0.07 (0.33)

NA

Abdel

1986

21

15(71)

68.7

Observation

10

4(40)

23.5

0.73 ± 0.49 (0.19)

NA

     

Laser

11

9(82)

38.8

0.92 ± 0.75 (0.12)

NA

Brown

1994

42

NA

70.0

Observation

26

24(92)

39.5

1.08 ± 0.91 (0.08)

NA

     

Laser

16

13(81)

42.9

1.08 ± 0.71 (0.08)

NA

Moosavi

2006

10

6(60)

71.0

Observation

9

5(56)

4.2

0.69 ± 0.86 (0.2)

NA

    

81.0

Laser

1

1(100)

4

1 (0.1)

NA

Tsujikawa

2009

13

10(77)

74.3

Observation

2

2(100)

8

0.41 ± 0.16 (0.39)

418.00 ± 145.66

     

Laser

11

6(55)

18

0.50 ± 0.27 (0.32)

438.55 ± 130.33

Cho

2013

23

19(82)

71.0

Observation

12

2(17)

10.5

1.36 ± 0.72 (0.04)

367.00 ± 105.68

     

Anti-VEGF

11

4(36)

11.2

0.86 ± 0.56 (0.14)

466.73 ± 128.86

Koinzer

2015

31

22(71)

75.4

Observation

16

1(6)

31.3

0.48 ± 0.40 (0.33)

NA

     

Laser

15

6(40)

37.2

0.55 ± 0.37 (0.28)

NA

Meyer

2015

27

22(81)

76.5

Observation

14

7(50)

21.8

0.79 ± 0.59 (0.16)

NA

     

Laser

13

0(0)

25.1

1.14 ± 0.70 (0.72)

NA

Cahuzac

2016

12

10(83)

75.1

Observation

5

1(20)

7.7

1.36 ± 0.92 (0.04)

561.60 ± 269.72

     

Laser

3

3(100)

7.7

0.50 ± 0.17 (0.32)

494.67 ± 108.09

     

Anti-VEGF

4

4(100)

7.7

1.50 ± 0.42 (0.03)

735.50 ± 184.21

PUMCH

2022

14

11(79)

71.6

Observation

5

2(40)

9

0.18 ± 0.20 (0.66)

260.40 ± 89.98

     

Laser

4

4(100)

2.75

0.58 ± 0.33 (0.26)

377.50 ± 85.25

     

Anti-VEGF

5

1(20)

5.6

1.16 ± 0.78 (0.07)

490.20 ± 210.50

Total

224

NA

72.4 ± 8.9

Observation

124

66(53)

27

0.82 ± 0.75 (0.14)

389.58 ± 175.27

     

Laser

80

48(60)

24.6

0.74 ± 0.66 (0.18)

407.50 ± 103.03

     

Anti-VEGF

20

9(45)

8.9

1.11 ± 0.63 (0.07)

500.74 ± 177.76

  1. CMT Central macular thickness, NA Not applicable, VA Visual acuity