Table 1 The basic clinical information and ocular surface parameters of AIBD patients and non-AIBD controls

Subjects (n)

25

24

Age (years)

55.16 ± 12.69

53.25 ± 16.31

0.649

Gender, n (%)

0.316

 Male

14 (56.0%)

10 (36.0%)

 Female

11 (44.0%)

14 (64.0%)

OSDI score

36.25 ± 25.33

21.29 ± 18.63

0.023

OSDI level, n (%)

0.029

 0 (0–12)

6 (24.0%)

11 (45.8%)

 1 (13–22)

4 (16.0%)

5 (20.8%)

 2 (23–32)

0 (0.0%)

2 (8.3%)

 3 (≥ 33)

15 (60.0%)

6 (25.0%)

Eyes (n)

50

48

Schirmer I test (mm/5 min)

8.42 ± 4.86

12.50 ± 9.00

0.006

Schirmer I test level, n (%)

0.594

  ≤ 5 mm/5 min

16 (32.0%)

13 (27.1%)

  > 5 mm/5 min

34 (68.0%)

35 (72.9%)

TBUT (s)

5.68 ± 3.37

7.42 ± 4.52

0.033

TBUT level, n (%)

 < 0.001

  ≤ 10 s

47 (94.0%)

31 (64.6%)

  > 10 s

3 (6.0%)

17 (35.4%)

Corneal fluorescein staining, n (%)

 < 0.001

 Normal (grade 0)

34 (68.0%)

46 (95.8%)

 Abnormal (≥ grade 1)

16 (32.0%)

2 (4.2%)

LIPCOF grade, n (%)

0.147

 0- No conjunctival fold

20 (40.0%)

29 (60.4%)

 1- One permanent and clear fold

8 (16.0%)

6 (12.5%)

 2- Two permanent and clear fold

11 (22.0%)

4 (8.3%)

 3- More than 2 permanent and clear parallel fold

11 (22.0%)

9 (18.8%)

Meibomian gland secretion, n (%)

0.420

 0- Clear fluid

20 (40.0%)

23 (48.9%)

 1- Cloudy fluid

23 (46.0%)

18 (38.3%)

 2- Granular and cloudy fluid

5 (10.0%)

6 (12.8%)

 3- Toothpaste like opaque or harder

2 (4.0%)

0 (0.0%)

Symblepharon presence, n (%)

0.004

 Normal

42 (84.0%)

48 (100.0%)

 Abnormal

8 (16.0%)

0 (0.0%)

Cornea clarity, n (%)

0.013

 Normal

44 (88.0%)

48 (100.0%)

 Abnormal

6 (12.0%)

0 (0.0%)

Dry eye level, n (%)

0.001

 No dry eye

2 (8.0%)

3 (12.5%)

 Grade 1

2 (8.0%)

11 (45.8%)

 Grade 2

3 (12.0%)

5 (20.8%)

 Grade 3

14 (56.0%)

5 (20.8%)

 Grade 4

4 (16.0%)

0 (0.0%)