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Table 1 Clinical characteristics of the Ologen-augmented (Oloxen) and non-augmented (Xen) groups during standalone XEN gel stent implantation

From: Comparison of surgical outcomes with and without Ologen collagen matrix augmentation during XEN gel stent implantation

 

Oloxen (n = 42)

Xen (n = 30)

p-value

Age, years (mean ± SD)

59.81 ± 15.62

58.10 ± 15.93

0.651*

Gender, n, male:female (%)

26:16 (61.9%:38.1%)

19:11(63.3%:36.7%)

0.902†

Laterality, n, OD:OS (%)

17:25 (40.5%:59.5%)

16:14 (53.3%:46.7%)

0.280†

HTN, n, yes:no (%)

14:28 (33.3%:66.7%)

11:19 (36.7%:63.3%)

0.770†

DM, n, yes:no (%)

10:32 (23.8%:76.2%)

5:25 (16.7%:83.3%)

0.462†

Preoperative visual acuity, logMAR (mean ± SD)

0.34 ± 0.43

0.56 ± 0.51

0.059*

Preoperative intraocular pressure, mmHg (mean ± SD)

17.60 ± 5.87

20.47 ± 6.46

0.054*

Prior glaucoma surgery, n, yes:no (%)

5:37 (11.9%:88.1%)

4:26(13.3%:86.7%)

0.858†

Number of preoperative anti-glaucoma medications, n (mean ± SD)

3.57 ± 0.83

3.67 ± 1.32

0.709*

Preoperative diagnosis (%)

  

0.770†

Primary open-angle glaucoma

28 (66.7%)

19 (63.3%)

 

Secondary open-angle glaucoma

14 (33.3%)

11 (36.7%)

 

Lens, n, phakic:pseudophakic (%)

20:22 (47.6%:52.4%)

12:18 (40.0%:60.0%)

0.532†

CCT, (mean ± SD)

531.42 ± 46.76

535.27 ± 37.99

0.786*

ECD, (mean ± SD)

2340.36 ± 481.67

2233.23 ± 584.71

0.398*

Axial length, mm, (mean ± SD)

25.05 ± 2.19

25.91 ± 2.41

0.162*

RNFL thickness, (mean ± SD)

66.50 ± 9.86

71.56 ± 10.67

0.068*

VFI, (mean ± SD)

55.73 ± 25.11

58.89 ± 30.40

0.654*

MD, (mean ± SD)

-15.73 ± 7.90

-14.57 ± 9.15

0.590*

PSD, (mean ± SD)

9.93 ± 3.45

8.35 ± 4.75

0.154*

  1. Abbreviations HTN Hypertension, DM Diabetic mellitus, CCT Central corneal thickness, ECD Endothelial cell density, RNFL Retinal nerve fiber layer, VFI Visual field index, MD Mean deviation, PSD Pattern standard deviation
  2. * Student’s t-test
  3. †Chi-square test