Skip to main content

Table 2 Results of OCT-A evaluation: Superficial (SPF) and deep (D) vascular density in the fovea, parafovea, and the whole image. Non-flow area and foveal avascular zone (FAZ). Data are shown as mean (SEM)

From: Atrophy of retinal vessels in neovascular age-related macular degeneration following long-term treatment with 20 intravitreal anti-VEGF injections

 

AMD 20x

AMD one year

Control

p value

p (AMD 20 × vs AMD one year)

p (AMD 20 × vs Control)

p (AMD one year vs Control)

Scan quality

7.0 (0.26)

7.2 (0.21)

7.78 (0.19)

0.0492

ns

ns

ns

CRT (um)

274.4 (17.39)

296.6 (9.936)

259.4 (2.701)

0.0036

ns

ns

**

SPF fovea (%)

16.82 (1.778)

25,36 (1,856)

25.67 (1.143)

0.0022

*

**

ns

SPF parafovea (%)

41.16 (1.064)

45.06 (1.067)

49.77 (1.142)

 < 0,0001

*

***

**

SPF whole (%)

38.85 (1.015)

37.19 (1.159)

45.29 (0.751)

 < 0,0001

ns

**

**

D fovea (%)

28.81 (1.991)

31.89 (1.386)

36.24 (0.4046)

0.0033

ns

**

*

D parafovea (%)

47.03 (1.727)

47.41 (0.914)

49.92 (0.156)

0.0774

ns

ns

ns

D whole (%)

44.24 (1.439)

45.01 (0.897)

47.31 (0.278)

0.0875

ns

ns

ns

Non-flow (mm2)

0.502 (0.0356)

0.504 (0.0484)

0.318 (0.0231)

0.0003

ns

***

**

FAZ (mm2)

0.356 (0.257)

0.349 (0.208)

0.221 (0.191)

0.0008

ns

**

**

  1. Group AMD 20x: Long-term treatment of at least 20 IVI
  2. Group one year. One year of T&E protocol treatment
  3. *p < 0.05, **p < 0.01, *p < 0.001, ns: non-significant (Kruskal–Wallis test, Dunn's Multiple Comparison Test)