Table 4 The results of the univariate and multivariate Cox regression analysis

Age

 < 0.001

 < 0.001

 <60

Ref

Ref

  ≥ 60

3.508(1.904–6.464)

3.146(1.699–5.826)

Year of diagnosis

0.008

0.054

 1992–2002

Ref

 2003–2012

0.524(0.333–0.826)

 2013–2018

0.473(0.251–0.89)

Sex

0.758

 Male

 Female

Race

0.189

 White

 Others

Laterality

0.051

0.115

 Unilateral

 Bilateral

 Unknown

Primary site

0.004

0.15

 Retina

Ref

 Choroid

0.156(0.047–0.52)

 Ciliary body

0.286(0.124–0.662)

 Vitreous

0.288(0.137–0.606)

Pathological type

 < 0.001

0.008

 DLBCL

Ref

Ref

 MALT

0.144(0.065–0.322)

0.233(0.101–0.534)

 NHL, NOS

0.587(0.325–1.062)

0.823(0.439–1.543)

 Other/unclassified^b

0.59(0.361–0.964)

0.813(0.489–1.353)

Ann arbor stage

0.057

 I to II

 III to IV

 Unknown

Surgery

0.441

 Performed

 No/unknown

Radiotherapy

0.362

 Performed

 No/unknown

Chemotherapy

 < 0.001

0.003

 Performed

Ref

Ref

 No/unknown

0.415(0.273–0.632)

0.498(0.316–0.785)