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Table 1 Summary of this case series

From: Neuro-ophthalmologic symptoms after coronavirus disease 2019 vaccination: a retrospective study

Case

Age (years)

Sex

Vaccine

Days after vaccine

Symptoms

Manifestations

Treatment and outcome

1

56

M

Pfizer-BioNTech #1

0

Binocular diplopia, left ptosis, left frontal headache

Left third nerve palsy

Total resolution within 3 months (aspirin started)

2

57

F

Pfizer-BioNTech #2

14

Binocular diplopia

Left fourth nerve palsy

Residual left hypertropia of 3 PD (symptoms persisted for > 3 months)

3

81

F

Pfizer-BioNTech #2

28

Binocular vertical diplopia

Left sixth nerve palsy

Follow-up loss (presumed to have had spontaneous resolution)

4

70

F

Pfizer-BioNTech #1

19

Binocular diplopia, headache

Right sixth nerve palsy

Spontaneous total resolution of symptoms within 18 days (relied on patient’s statements, no tests were performed)

5

67

F

AZ #1

3

Binocular diplopia, left ptosis

Right fourth nerve palsy

Residual right hypertropia of 3 PD, prism glasses prescribed (symptoms persisted for > 6 months)

6

60

M

AZ #1

2

Binocular horizontal diplopia, occipital headache

Left fourth nerve palsy

Spontaneous total resolution within 5 months

7

69

M

AZ #1

12

Binocular diagonal diplopia

Right fourth nerve palsy

Total resolution within 1 day (aspirin started)

8

68

M

AZ #1

23

Binocular vertical diplopia, dizziness, right facial numbness

Left fourth nerve palsy

Total resolution within 6 days (dual antiplatelet therapy started)

9

65

F

AZ #1

3

Binocular diplopia (subjective)

Diplopia due to undetermined cause

Spontaneous recovery within 6 weeks

10

73

F

Moderna #1

0

Sudden loss of vision in the OD, severe discharge in the OS, left temporal headache, myalgia, dizziness, nausea, cough, rhinorrhea

Sudden loss of vision with increased IOP and orbital cellulitis

Recovery of vision after drop in IOP in 1 day, resolution of orbital cellulitis after intravenous antibiotics and corticosteroid for 5 days

  1. M Male, F Female, #1 First dose, #2 Second dose, OD Oculus dexter, OS Oculus sinister, AZ AstraZeneca, IOP Intraocular pressure, PD Prism diopters