From: Neuro-ophthalmologic symptoms after coronavirus disease 2019 vaccination: a retrospective study
Case | Age (years) | Sex | Vaccine | Days after vaccine | Symptoms | Manifestations | Treatment and outcome |
---|---|---|---|---|---|---|---|
1 | 56 | M | Pfizer-BioNTech #1 | 0 | Binocular diplopia, left ptosis, left frontal headache | Left third nerve palsy | Total resolution within 3Â months (aspirin started) |
2 | 57 | F | Pfizer-BioNTech #2 | 14 | Binocular diplopia | Left fourth nerve palsy | Residual left hypertropia of 3 PD (symptoms persisted for > 3 months) |
3 | 81 | F | Pfizer-BioNTech #2 | 28 | Binocular vertical diplopia | Left sixth nerve palsy | Follow-up loss (presumed to have had spontaneous resolution) |
4 | 70 | F | Pfizer-BioNTech #1 | 19 | Binocular diplopia, headache | Right sixth nerve palsy | Spontaneous total resolution of symptoms within 18 days (relied on patient’s statements, no tests were performed) |
5 | 67 | F | AZ #1 | 3 | Binocular diplopia, left ptosis | Right fourth nerve palsy | Residual right hypertropia of 3 PD, prism glasses prescribed (symptoms persisted for > 6 months) |
6 | 60 | M | AZ #1 | 2 | Binocular horizontal diplopia, occipital headache | Left fourth nerve palsy | Spontaneous total resolution within 5Â months |
7 | 69 | M | AZ #1 | 12 | Binocular diagonal diplopia | Right fourth nerve palsy | Total resolution within 1Â day (aspirin started) |
8 | 68 | M | AZ #1 | 23 | Binocular vertical diplopia, dizziness, right facial numbness | Left fourth nerve palsy | Total resolution within 6Â days (dual antiplatelet therapy started) |
9 | 65 | F | AZ #1 | 3 | Binocular diplopia (subjective) | Diplopia due to undetermined cause | Spontaneous recovery within 6Â weeks |
10 | 73 | F | Moderna #1 | 0 | Sudden loss of vision in the OD, severe discharge in the OS, left temporal headache, myalgia, dizziness, nausea, cough, rhinorrhea | Sudden loss of vision with increased IOP and orbital cellulitis | Recovery of vision after drop in IOP in 1Â day, resolution of orbital cellulitis after intravenous antibiotics and corticosteroid for 5Â days |