Table 2 GSEA pathways up-regulated and down-regulated due to DR2 group
Gene sets | SIZE | NES | NOM p-val | FDR q-val |
|---|---|---|---|---|
Up-regulated gene sets in DR2 group | ||||
HALLMARK_INTERFERON_GAMMA_RESPONSE | 194 | 1.78 | 0.000 | 0.000 |
HALLMARK_COAGULATION | 133 | 1.69 | 0.000 | 0.000 |
HALLMARK_INTERFERON_ALPHA_RESPONSE | 95 | 1.69 | 0.000 | 0.000 |
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 198 | 1.68 | 0.000 | 0.000 |
HALLMARK_ANGIOGENESIS | 36 | 1.67 | 0.000 | 0.000 |
HALLMARK_IL6_JAK_STAT3_SIGNALING | 83 | 1.62 | 0.000 | 0.000 |
HALLMARK_INFLAMMATORY_RESPONSE | 198 | 1.56 | 0.000 | 0.000 |
HALLMARK_ALLOGRAFT_REJECTION | 195 | 1.53 | 0.000 | 0.000 |
HALLMARK_COMPLEMENT | 198 | 1.38 | 0.000 | 0.042 |
HALLMARK_TNFA_SIGNALING_VIA_NFKB | 199 | 1.37 | 0.000 | 0.075 |
HALLMARK_IL2_STAT5_SIGNALING | 197 | 1.35 | 0.000 | 0.085 |
HALLMARK_XENOBIOTIC_METABOLISM | 198 | 1.26 | 0.000 | 0.234 |
HALLMARK_APOPTOSIS | 158 | 1.25 | 0.000 | 0.244 |
Down-regulated gene sets in the DR2 group | ||||
HALLMARK_PANCREAS_BETA_CELLS | 40 | −1.91 | 0.000 | 0.000 |