Table 1 Baseline demographic and ocular characteristics of the eyes completed the study protocol
Variables | Total n = 58 | Monotherapy arm (three monthly IVB) n = 32 | Combination arm (single dose of SCTA + three monthly IVB) n = 26 | Between group analysis a |
|---|---|---|---|---|
Age, year | ||||
Mean (SD) | 62.6 (5.9) | 62.8 (5.8) | 62.4 (6.2) | P = 0.80 |
Median (IQR) | 63 (50–73) | 63 (53–73) | 62.5 (50–73) | |
Sex, n (%) | ||||
Male | 19 (32.8%) | 9 (28.1%) | 10 (38.5%) | P = 0.29 |
Female | 39 (67.2%) | 23 (71.9%) | 16 (61.5%) | |
Diabetes duration, year | ||||
Mean (SD) | 13.2 (5.4) | 13.5 (5.7) | 12.7 (5.1) | P = 0.59 |
Median (IQR) | 12.5 (2–25) | 12.5 (2–25) | 12.5 (4–22) | |
Previous IVB injection % | ||||
Yes | 27 (46.6%) | 15 (46.9%) | 12 (46.2%) | P = 0.87 |
No | 31 (53.4%) | 17 (53.1%) | 14 (53.8%) | |
No. of previous IVB injections | ||||
Mean (SD) | 1.8 (2.4) | 1.8 (2.4) | 1.7 (2.5) | P = 0.85 |
Median (IQR) | 0 (0–9) | 0 (0–9) | 0 (0–9) | |
Lens status | ||||
Natural (phakic) | 41 (70.7%) | 23 (71.9%) | 18 (69.2%) | P = 0.83 |
Prosthetic IOL | 17 (29.3%) | 9 (28.1%) | 8 (30.8%) | |
Stage of diabetic retinopathy, n (%) | ||||
Mild to moderate NPDR | 9 (15.5%) | 4 (12.5%) | 5 (19.2%) | |
Sever NPDR | 45 (77.6%) | 26 (81.3%) | 19 (73.1%) | P = 0.75 |
Regressed PDR | 4 (6.9%) | 2 (6.2%) | 2 (7.7%) | |