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Table 1 OCTA parameters and MLC density in control and DR groups

From: Proliferative diabetic retinopathy and diabetic macular edema are two factors that increase macrophage-like cell density characterized by en face optical coherence tomography

 

Control

DR

  
 

NPDR

PDR

P††

P*

DME, n (%)

–

50 (41.7)

27 (38.57)

0.675#

–

PRP, n (%)

–

31 (25.8)

22 (31.42)

0.407#

–

MLC density (cells/mm2), median (IQR)

6.48 (6.71)

6.14 (8.78)

8.97 (8.40)

0.013†

0.025

VD of DCP (%), median (IQR)

55.88 (3.95)

47.88 (8.05)

43.68 (11.62)

< 0.001†

< 0.001

VD of SCP (%), mean ± SD

50.07 ± 5.01

51.00 ± 4.82

51.42 ± 6.91

0.455†

0.35

MRT (μm), median (IQR)

291.49 (16.38)

316.79 (52.83)

319.52 (53.85)

0.431†

< 0.001

CFT (μm), median (IQR)

205.28 (18.54)

221.08 (115.19)

215,93 (54.90)

0.432†

< 0.001

  1. DME diabetic macular edema, PPR panretinal photocoagulation, MLC macrophage-like cell, VD vessel density, DCP deep capillary plexus, SCP superficial capillary plexus, MRT mean retina thickness, CFT central fovea thickness, SD standard deviation, IQR interquartile range
  2. ††comparison between NPDR and PDR
  3. †Mann-Whitney U test
  4. #Chi-square test
  5. *comparison among control group, NPDR and PDR eyes using nonparametric Kruskal–Wallis H test