Skip to main content

Table 1 Characteristics of the subjects by hypertensive retinopathy groupa

From: Positive correlation between hypertensive retinopathy and albuminuria in hypertensive adults

Characteristics

Overall

Normal

Grade 1

Grade 2

Grade 3

p

N

2964

693

1747

446

78

 

Age, years

63.5 ± 7.3

63.4 ± 7.1

63.7 ± 7.5

62.4 ± 6.7

63.5 ± 7.4

0.008

Male, N (%)

1070 (36.1)

228 (32.9)

649 (37.2)

164 (36.8)

29 (37.2)

0.254

BMI, kg/m2

25.7 ± 3.8

25.6 ± 3.7

25.6 ± 3.8

26.1 ± 3.9

26.0 ± 4.4

0.035

Treatment Group, N (%)

     

0.590

 Enalapril

1255 (50.7)

293 (51.1)

744 (51.0)

190 (50.3)

28 (42.4)

 

 Enalapril + folic acid

1222 (49.3)

280 (48.9)

716 (49.0)

188 (49.7)

38 (57.6)

 

MTHER C677T, N (%)

     

0.668

 CC

673 (22.9)

164 (23.8)

381 (22.1)

108 (24.3)

20 (25.6)

 

 CT

1469 (50.0)

344 (50.0)

872 (50.6)

211 (47.4)

42 (53.8)

 

 TT

794 (27.0)

180 (26.2)

472 (27.4)

126 (28.3)

16 (20.5)

 

Smoking status, N (%)

     

0.725

 Never

2094 (71.1)

494 (71.9)

1236 (71.1)

307 (69.1)

57 (74.0)

 

 Former

284 (9.6)

65 (9.5)

170 (9.8)

40 (9.0)

9 (11.7)

 

 Current

569 (19.3)

128 (18.6)

333 (19.1)

97 (21.8)

11 (14.3)

 

Alcohol consumption, N (%)

     

0.659

 Never

2089 (73.8)

509 (76.3)

1207 (72.7)

317 (73.7)

56 (74.7)

 

 Former

168 (5.9)

33 (4.9)

106 (6.4)

26 (6.0)

3 (4.0)

 

 Current

575 (20.3)

125 (18.7)

347 (20.9)

87 (20.2)

16 (21.3)

 

Diabetes, N (%)

68 (2.3)

11 (1.6)

43 (2.5)

9 (2.0)

5 (6.6)

0.045

Medication use, N (%)

      

 Antihypertensive treatment

2797 (95.1)

643 (93.9)

1657 (95.5)

426 (95.9)

71 (92.2)

0.179

SBP, mmHg

137.7 ± 17.5

135.9 ± 16.6

137.9 ± 17.6

139.1 ± 18.2

140.4 ± 18.2

0.006

DBP, mmHg

83.0 ± 10.7

82.2 ± 10.1

82.8 ± 10.7

84.4 ± 11.6

84.9 ± 11.5

0.002

Laboratory results

      

 TCHO, mmol/L

5.4(4.7,6.0)

5.3(4.7,6.0)

5.4(4.8,6.0)

5.5(4.7,6.1)

5.4(4.7,6.1)

0.810

 TG, mmol/L

1.5(1.1,2.2)

1.4(1.1,2.2)

1.5(1.1,2,2)

1.6(1.1,2,2)

1.5(1.0,2.4)

0.252

 FBG, mmol/L

5.8(5.4,6.5)

5.8(5.4,6.4)

5.8(5.4,6.5)

5.8(5.3,6.6)

5.9(5.4,8.9)

0.148

 UA, μmol/L

314.0(55.8,74.3)

303(259,367)

319(269,379)

315(267,380)

319.5(266,384.5)

0.005

 Scr, μmol/L

64.3(55.8,74.3)

62.0(54.5,71.9)

64.8(56.4,75.1)

65.2(56.0,75.1)

64.6(52.8,71.1)

 < 0.001

 Folate, ng/mL

14.8(10.8,19.8)

14.8(11.0,19.6)

14.7(10.6,19.9)

14.8(10.8,19.3)

15.6(11.4,20.6)

0.709

 HCY, μmol/L

12.0(10.1,14.8)

12.0(10.0,14.2)

12.2(10.2,14.9)

12.0(10.2,15.1)

12.0(10.6,13.8)

0.046

 eGFR, mL/min/1.73 m2

92.6(83.6,99.1)

93.7(86.3,99.7)

92.0(83.0,98.7)

92.3(83.2,99.4)

92.7(82.6,99.1)

0.007

 UACR, mg/g

10.5(7.2,17.1)

10.1(7.1,16.8)

10.4(7.2,16.5)

10.9(7.7,18.5)

13.7(7.8,22.6)

0.003

Albuminuria, N (%)

330 (11.1)

55 (7.9)

200 (11.4)

62 (13.9)

13 (16.7)

0.004

  1. BMI Body mass index, MTHER Methylenetetrahydrofolate reductase, SBP Systolic blood pressure, DBP Diastolic blood pressure, TCHO Total cholesterol, TG Triglyceride, FBG Fasting blood glucose, UA Uric acid, Scr Serum creatinine, HCY Homocysteine, eGFR Estimated glomerular filtration rate, UACR Urinary albumin to creatinine ratio
  2. aFor continuous variables, values are presented as the mean ± standard deviation or median (interquartile range). For categorical variables, values are presented as frequencies
Back to article page

BMC Ophthalmology

ISSN: 1471-2415

Contact us