Positive correlation between hypertensive retinopathy and albuminuria in hypertensive adults

BMC Ophthalmology

Table 2 The association between hypertensive retinopathy and UACR^a

Hypertensive retinopathy	N	UACR, mg/g Median (interquartile range)	Unadjusted model		Model I		Model II
Hypertensive retinopathy	N	UACR, mg/g Median (interquartile range)	β (95% CI)	p	β (95% CI)	p	β (95% CI)	p
Normal	693	10.1 (7.1,16.8)	ref		ref		ref
Grade 1	1747	10.4 (7.2,16.5)	1.53 (0.06,3.01)	0.042	1.72 (0.26,3.17)	0.021	1.42 (-0.12,2.95)	0.070
Grade 2	446	10.9 (7.7,18.5)	2.69 (0.69,4.68)	0.008	3.15 (1.18,5.12)	0.002	2.62 (0.56,4.67)	0.013
Grade 3	78	13.7 (7.8,22.6)	5.61 (1.69,9.54)	0.005	5.88 (2.01,9.76)	0.003	5.17 (1.13,9.20)	0.012
p for trend				< 0.001		< 0.001		0.001

UACR Urinary albumin to creatinine ratio, CI Confidence interval
^aModel I was adjusted for age, sex, and body mass index; Model II was adjusted for age, sex, body mass index, systolic blood pressure, diastolic blood pressure, methylenetetrahydrofolate reductase C677T polymorphisms, total cholesterol, triglycerides, fasting blood glucose, estimated glomerular filtration rate, folate, homocysteine, smoking status, alcohol consumption, and the use of antihypertensive drugs

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