Positive correlation between hypertensive retinopathy and albuminuria in hypertensive adults

BMC Ophthalmology

Table 3 The association between hypertensive retinopathy and albuminuria^a

Hypertensive retinopathy	N	Albuminuria N (%)	Unadjusted model		Model I		Model II
Hypertensive retinopathy	N	Albuminuria N (%)	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
Normal	693	55 (7.9)	ref		ref		ref
Grade 1	1747	200 (11.4)	1.50 (1.10,2.05)	0.011	1.51 (1.10,2.07)	0.011	1.57 (1.08,2.29)	0.019
Grade 2	446	62 (13.9)	1.87 (1.28,2.75)	0.001	1.99 (1.35,2.95)	< 0.001	2.02 (1.28,3.18)	0.002
Grade 3	78	13 (16.7)	2.32 (1.20,4.47)	0.012	2.37 (1.22,4.61)	0.011	2.12 (0.99,4.55)	0.053
p for trend				< 0.001		< 0.001		0.002

OR Odds ratio, CI Confidence intervals
^aModel I was adjusted for age, sex, and body mass index; Model II was adjusted for age, sex, body mass index, systolic blood pressure, diastolic blood pressure, methylenetetrahydrofolate reductase C677T polymorphisms, total cholesterol, triglycerides, fasting blood glucose, estimated glomerular filtration rate, folate, homocysteine, smoking status, alcohol consumption, and the use of antihypertensive drugs

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