Table 4 Clinician’s Global Evaluation of Treatment: End of Week 12†
ITT population | PP population | |||||
|---|---|---|---|---|---|---|
Treatment group | A | B | C | A | B | C |
Number of eyes graded | 96 | 98 | 96 | 60 | 64 | 56 |
Completely cleared | 14 (14.6%) | 2 (2.0%) | 4 (4.2%) | 14 (23.3%) | 2 (3.1%) | 4 (7.1%) |
~ 90% improvement | 21 (21.9%) | 23 (23.5%) | 21 (21.9%) | 19 (31.7%) | 23 (35.9%) | 17 (30.3%) |
~ 75% improvement | 11 (11.5%) | 18 (18.4%) | 29 (30.2%) | 9 (15.0%) | 16 (25.0%) | 21 (37.5%) |
~ 50% improvement | 13 (13.5%) | 17 (17.3%) | 11 (11.5%) | 13 (21.7%) | 17 (26.6%) | 11 (19.6%) |
~ 25% improvement | 3 (3.1%) | 3 (3.1%) | 3 (3.1%) | 3 (5.0%) | 3 (4.7%) | 3 (5.4%) |
Condition unchanged | 2 (2.1%) | 3 (3.1%) | 0 (0.0%) | 2 (3.3%) | 3 (4.7%) | 0 (0.0%) |
Condition worsened | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | - |
P-Value 1 | 0.1576 | 0.3075 | - | 0.1760 | 0.4363 | - |
P-Value 2 | 0.0278 | - | - | 0.0364 | - | - |