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Fig. 5 | BMC Ophthalmology

Fig. 5

From: A novel homozygous missense substitution p.Thr313Ile in the PDE6B gene underlies autosomal recessive retinitis pigmentosa in a consanguineous Pakistani family

Fig. 5

A The interaction of wild-type PDE6B and mutant type PDE6B with cGMP is shown. Surface representation of cGMP interactions with (a) wild type PDE6B and (b) mutant type PDE6B. 3D representation of cGMP (in purple) interactions with (c) wild type PDE6B and (d) mutant type PDE6B. B Depicts the interactions of wild-type PDE6B and mutant type PDE6B with wild type PDE6A. Surface representation of interactions between (a) wild type PDE6B (in green) with PDE6A (in cyan), and (b) mutant type PDE6B (in green) and PDE6A (in cyan). 3D interactions of PDE6A with (c) wild type PDE6B and (d) mutant type PDE6B

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BMC Ophthalmology

ISSN: 1471-2415

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