Fig. 3

Optical coherence tomographic findings (vertical sections) of a representative case showing ischemic retinal damage due to sustained high IOP during the NVG attack. This patient had undergone AGVI seven days after NVG diagnosis, and their final visual outcome was unfavorable. A is an OCT finding taken one year after diabetic PPV (three months before NVG diagnosis). B and C are OCT findings at the time of NVG diagnosis and three days after AGVI, respectively. Figures B and C shows inner retinal edema and hyper-reflectivity, suggesting retinal ischemia. D is an OCT photograph one year after the occurrence of NVG, and prominent thinning of inner retinal layers is confirmed. A-1 and B-1 are magnified images of A and B, respectively. The inner retinal layer includes the nerve fiber layer, ganglion cell layer, inner plexiform layer, and inner nuclear layer. The outer retinal layer includes the outer plexiform layer and photoreceptor layer. Measurements of the inner retinal layer (bold double-sided arrows) and outer retinal layer (double-sided arrows) were made 1 mm from the fovea. Among the inner retinal layers, progressive thinning was observed in the nerve fiber layer, and the ganglion cell layer (arrows) and the inner nuclear layer was relatively preserved (arrowheads). E and F show the average retinal thickness values (um) of A and D, respectively. The average retinal thickness values were obtained from the 1, 3, 6 mm thickness map of each quadrant (OCT, Spectralis OCT; Heidelberg Engineering, Heidelberg, Germany). The retinal thickness of the whole macula was markedly decreased one year after the NVG diagnosis