Total (n = 35) | Group 1 (n = 16) | Group 2 (n = 19) | P-value | |||||
---|---|---|---|---|---|---|---|---|
Baseline characteristics | ||||||||
Age (years) | 58.4 ± 10.3 | 58.4 ± 10.3 | 51.9 ± 10.2 | 0.246† | ||||
Sex (M/F) | 22/13 | 8/8 | 14/5 | 0.179‡ | ||||
Laterality (R/L) | 18/17 | 7/9 | 11/8 | 0.505‡ | ||||
VA (LogMAR) | ||||||||
BCVA before NVG diagnosis | 0.85 ± 0.62 | 0.88 ± 0.50 | 0.82 ± 0.71 | 0.483† | ||||
VA at the time of NVG diagnosis | 1.67 ± 0.79 | 2.13 ± 0.50 | 1.28 ± 0.71 | 0.008† | ||||
IOP at the time of NVG diagnosis (mmHg) | 40.2 ± 8.3 | 41.3 ± 8.3 | 39.3 ± 8.2 | 0.905† | ||||
Lens status (Phakic/Pseudophakic) | 5/30 | 3/13 | 2/17 | 0.642‡ | ||||
Non-surgical treatment and therapeutic response during the first week after NVG diagnosis | ||||||||
No. of IOP-lowering medications | 2.51 ± 0.69 | 2.13 ± 0.78 | 2.84 ± 0.36 | 0.005† | ||||
AC paracentesis (%) | 14 (40.0) | 6 (37.5) | 8 (42.1) | 1.000‡ | ||||
Anti-VEGF injections (%) | 27 (77.1) | 12 (75.0) | 15 (78.9) | 1.000‡ | ||||
Add PRP | 5 (14.3) | 1 (6.3) | 4 (21.1) | 0.347‡ | ||||
Last IOP within the first week (mmHg) | 30.2 ± 11.3 * | 38.7 ± 8.3 ** | 22.3 ± 7.2 *** | 0.000† | ||||
Delta IOP (mmHg) (IOP at the day of NVG diagnosis - IOP at the last day within the first week) | 11.3 ± 10.8 * | 3.0 ± 7.7 ** | 19.0 ± 6.8 *** | 0.000† | ||||
Delta IOP > 10 mmHg (%) | 16 (45.7) | 3 (23.1) | 13 (68.4) | 0.000‡ |