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Table 3 Factors affecting central vision loss after Ahmed glaucoma valve implantation in Group 1

From: Visual prognosis and surgical timing of Ahmed glaucoma valve implantation for neovascular glaucoma secondary to diabetic vitrectomy

 

Favorable visual outcome* (n = 9)

Unfavorable visual outcome (n = 7)

P-value

Age (years)

58.7 ± 11.4

58.0 ± 8.7

0.916†

Sex (M/F)

5/4

3/4

1.000‡

IOP (mmHg)

   

At the time of NVG diagnosis

41.0 ± 8.6

41.6 ± 7.8

0.874†

At the time of AGVI

41.4 ± 7.4

41.0 ± 7.5

0.791†

BCVA (LogMAR)

   

Before the diagnosis of NVG

0.74 ± 0.42

1.05 ± 0.55

0.238†

At the time of NVG diagnosis

2.23 ± 0.19

2.00 ± 0.23

0.032†

Early AGVI timing (%)

(less than one week from NVG diagnosis)

7 (77.8)

1 (14.3)

0.041‡

No. of IOP-lowering medications

2.0 ± 0.94

2.3 ± 0.45

0.678†

AC paracentesis (%)

6 (66.7)

6 (42.9)

1.000‡

Anti-VEGF injections (%)

5 (62.5)

5 (86.7)

0.585‡

Add PRP (%)

0 (0)

1 (14.3)

0.438‡

  1. *Favorable visual outcome : Comparing preoperative BCVA(sufficiently stable BCVA after the recovery from diabetic vitrectomy) and postoperative BCVA (the best result of the BCVA measurements during the one year follow-up period after AGVI), a favorable visual outcome was defined as a BCVA that deteriorated to less than 0.3 logMAR unit after AGVI.
  2. † Calculated using an independent t-test and Mann Whitney test
  3. ‡ Calculated using a Chi-Square test and Fisher’s Exact test
  4. Abbreviations: M, male; F, female; IOP, intraocular pressure; BCVA, best-corrected visual acuity; AGVI, Ahmed glaucoma valve implantation; NVG, neovascular glaucoma; AC, anterior chamber; Add PRP, additional pan-retinal photocoagulation
  5. Group 1, Group of NVG patients who maintained an IOP of 30 mmHg or more before AGVI despite initial non-surgical treatment, including maximum tolerable medical treatment.