Table 2 Genotype and allele frequencies of CLU rs2279590 C/T, rs11136000 C/T, rs1532278 C/T, and rs3087554 T/C SNPs in patients with PEG, patients with PEX, and the controls

rs2279590 C/T

Genotypes, n (%)

Recessive

0.88^a (0.56–1.38) 0.84^b (0.54–1.33) 1.10^c (0.69–1.76)

.570^a .460^b .690^c

CC

97 (40.6)

86 (35.8)

92 (38.3)

CT

97 (40.6)

110 (45.8)

97 (40.4)

Dominant

0.94^a (0.65–1.36) 1.12^b (0.77–1.62) 0.84^c (0.58–1.21)

.730^a .550^b .340^c

TT

45 (18.8)

44 (18.3)

51 (21.2)

Alleles, n (%)

C

291 (60.9)

282 (58.8)

281 (58.5)

0.91^a (0.70–1.18) 0.99^b (0.77–1.28) 0.92^c (0.71–1.19)

.460^a > .999 .500^c

T

187 (39.1)

198 (41.2)

199 (41.5)

rs11136000 C/T

Genotypes, n (%)

Recessive

0.78^a (0.49–1.22) 0.77^b (0.49–1.22) 1.06^c (0.66–1.71)

.270^a .270^b .810^c

CC

99 (41.4)

91 (37.9)

92 (38.3)

CT

98 (41.0)

107 (44.6)

96 (40.0)

Dominant

0.92^a (0.63–1.32) 1.02^b (0.71–1.48) 0.88^c (0.61–1.27)

.640^a .900^b .490^c

TT

42 (17.6)

42 (17.5)

52 (21.7)

Alleles, n (%)

C

296 (61.9)

289 (60.2)

280 (58.3)

0.86^a (0.66–1.12) 0.93^b (0.72–1.20) 0.93^c (0.72–1.21)

.260^a .550^b .590^c

T

182 (38.1)

191 (39.8)

200 (41.7)

rs1532278 C/T

Genotypes, n (%)

Recessive

0.80^a (0.51–1.26) 0.79^b (0.50–1.25) 1.06^c (0.66–1.71)

.340^a .320^b .800^c

CC

99 (41.4)

91 (37.9)

93 (38.8)

CT

98 (41.0)

107 (44.6)

96 (40.0)

Dominant

0.93^a (0.64–1.34) 1.04^b (0.72–1.50) 0.88^c (0.61–1.27)

.680^a .840^b .490^c

TT

42 (17.6)

42 (17.5)

51 (21.2)

Alleles, n (%)

C

296 (61.9)

289 (60.2)

282 (58.8)

0.88^a (0.68–1.14) 0.94^b (0.73–1.22) 0.93^c (0.72–1.21)

.320^a .650^b .590^c

T

182 (38.1)

191 (39.8)

198 (41.2)

rs3087554 T/C

Genotypes, n (%)

Recessive

1.65^a (0.57–4.76) 2.43^b (0.92–6.44) 0.63^c (0.27–1.49)

.350^a .060^b .290^c

TT

166 (69.5)

170 (70.8)

180 (75.0)

TC

64 (26.8)

56 (23.3)

54 (22.5)

Dominant

1.33^a (0.89–2.00) 1.23^b (0.82–1.84) 1.06^c (0.71–1.56)

.160^a .320^b .790^c

CC

9 (3.8)

14 (5.8)

6 (2.5)

Alleles, n (%)

T

396 (82.8)

396 (82.5)

414 (86.2)

1.30^a (0.91–1.85) 1.33^b (0.94–1.89) 0.98^c (0.70–1.36)

.140^a .110^b  > .999^c

C

82 (17.2)

84 (17.5)

66 (13.8)