Fig. 3

Histology of the intraoperatively resected iris is shown in A and B. A Giemsa stained image shows no obvious papillary structures (A). After de-melaninization, pigment epithelial cells show little nuclear atypia and no highly atypical cells causing stromal infiltration. The stroma is edematous and slightly infiltrated by chronic inflammatory cells. No findings suggest malignancy (B). A slit-lamp image and morphology of the filtering bleb by AS-OCT 7 years postoperatively are shown in C and D. A photograph of the anterior segment shows a well-maintained filtration bleb (C). The filtration bleb contains a large reticular layer and is in good condition in the AS-OCT bleb image (dotted arrow in Fig. C) (D). An anterior image shows no hyperemia or obvious inflammation. Posterior iris synechiae are visualized around the pupil (E). The multiple iris nodules at disease onset resolved, and the nodules are irregular (F). An anterior image of the fellow eye shows no hyperemia or obvious inflammation (G), but small linear keratic precipitates are seen (white arrows in Fig. H) (H)