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Table 1 Changes in clinical parameters for patients with meibomian gland dysfunction between before and three weeks after four sessions of intense pulsed light treatment combined with the meibomian gland expression

From: Intense pulsed-light treatment improves objective optical quality in patients with meibomian gland dysfunction

Parameter

Pre-Treatment

Post-Treatment

P-value

BCVA (logMAR)

0.04 ± 0.07

0.03 ± 0.05

0.08

Optical quality parameters

   

OSI

3.37 ± 3.05

1.45 ± 0.92

< 0.001

MTF cutoff

21.06 ± 12.30

31.62 ± 9.58

< 0.001

Strehl ratio

0.12 ± 0.06

0.18 ± 0.04

< 0.001

Lipid layer thickness (nm)

   

Mean

75.30 ± 25.03

82.73 ± 20.51

0.031

Maximum

89.48 ± 18.70

95.00 ± 12.37

0.021

Minimum

61.90 ± 28.73

67.64 ± 25.92

0.207

Partial blinking rate

0.51 ± 0.42

0.39 ± 0.40

0.037

MG expressibility

2.06 ± 0.72

0.92 ± 0.64

< 0.001

TBUT (sec)

3.18 ± 1.46

6.60 ± 1.96

< 0.001

CFS score

1.18 ± 0.82

0.61 ± 0.55

< 0.001

Schirmer I test (mm)

8.41 ± 1.69

9.64 ± 1.72

< 0.001

OSDI score

31.46 ± 6.29

23.26 ± 5.96

< 0.001

  1. The results are expressed as mean and standard deviation. BCVA, best corrected visual acuity; OSI, objective scatter index; MTF, modulation transfer function; logMAR, logarithm of the minimum angle of resolution; MG, meibomian gland; Corneal and conjunctival fluorescein staining (scale from 0 to 9); TBUT, tear break-up time; CFS, OSDI, ocular surface disease index questionnaire