From: Comparison of epidemiologic factors and eye manifestations of twin children with controls
Parameters | Levels | Groups | P-value | ||||
---|---|---|---|---|---|---|---|
Twins (n = 180) | Non- twins (n = 182) | ||||||
Monozygotic (n = 54) | Dizygotic (n = 126) | P-value | Total (180) | ||||
Sex (%) | Female | 36 (66.7%) | 72 (57.1%) | 0.232** | 108 (60.0%) | 84 (46.2%) | 0.01** |
Male | 18 (33.3%) | 54 (42.9%) | 72 (40.0%) | 98 (53.8%) | |||
Age | mean ± SD | 7.44 ± 3.71 | 6.94 ± 4.65 | 0.478*** | 7.08 ± 4.42 | 7.58 ± 3.99 | 0.253*** |
median (Range) | 7 (1 to 14) | 7 (1 to 20) | 7 (1 to 20) | 7 (1 to 16) | |||
Incomplete Gestational age | 17 (31.5%) | 39 (30.9%) | 0.825** | 56 (31.1%) | 14 (7.7%) | < 0.001** | |
Low Birth weight (< 1500gr) | 9 (16.7%) | 13 (10.3%) | 0.233** | 22 (12.2%) | 5 (2.7%) | 0.001** | |
H/O Neonatal jaundice | 25 (46.3%) | 78 (61.9%) | 0.052** | 103 (57.2%) | 63 (34.6%) | < 0.001** | |
H/O Seizure | 2 (3.7%) | 4 (3.2%) | 0.864* | 6 (3.3%) | 4 (2.2%) | 0.54* | |
H/O Incubator | 31 (57.4%) | 74 (58.7%) | 0.777** | 105 (58.3%) | 7 (3.8%) | < 0.001** | |
Ocular anomaly | Ant. seg. anomaly | 0 (0.0%) | 2 (1.6%) | 0.354* | 2 (1.1%) | 0 (0.0%) | 0.62* |
Post. seg. anomaly | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (0.5%) | |||
H/O strabismus surgery | 10 (18.5%) | 16 (12.7%) | 0.426** | 26 (14.5%) | 3 (1.6%) | < 0.001** | |
Twins in close family | 19 (35.2%) | 88 (69.8%) | < 0.001* | 107 (59.4%) | - | - | |
Neurological delay | 2 (3.7%) | 4 (3.2%) | 0.864* | 6 (3.3%) | 4 (2.2%) | 0.536* | |
Physical delay | 4 (7.4%) | 3 (2.4%) | 0.113** | 7 (3.9%) | 4 (2.2%) | 0.38** |