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Fig. 2 | BMC Ophthalmology

Fig. 2

From: A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection

Fig. 2

Schematic diagram of 4 grades of ASI in the grading system mentioned in this article. A Grade 0. When a small amount of HA microspheres blocks the ASC, there is usually no definite ciliary function damage, but may be other manifestations of mASI such as uveitis, pupil irregularity. B Grade 1. If the HA microspheres are dense in a certain quadrant, it is possible to cause segmental iris atrophy, usually with mild ciliary process dysfunction (CHS), usually with clinical characteristics of mydriasis, uveitis. C Grade 2. When a large amount of HA microspheres blocks the ASC, it is easy to cause extensive iris atrophy. If no 360-degree circumferential iris atrophy occurs, there may present with moderate ciliary function damage (hypotony), with clinical characteristics of mydriasis, Tyndall effect, severe uveitis, corneal edema, but usually no subsequent PB. D Grade 3. When a large amount of HA microspheres blocks the ASC, resulting in 360-degree circumferential iris atrophy, there may present with severe ciliary function damage, with clinical characteristics of mydriasis, severe uveitis, corneal edema, cataract and subsequent PB. ASI, anterior segment ischemia; HA, hyaluronic acid; ASC, anterior segment circulation; CHS, ciliary hyposecretion; PB, phthisis bulbi

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