Fig. 1

Representative images of acute SJS/TEN patients. a Ocular surface image of a patient with acute SJS (number 7 patient in Table 1). Diffuse erythema around both eyelids, conjunctival hyperemia, and edema of both upper eyelids. The image was taken on the fourth day after the onset of clinical symptoms. b Ocular surface image of a patient with acute TEN (number 9 patient in Table 1). Conjunctival hyperemia and edema of bulbar conjunctiva in both eyes. The image was taken on the fifth day after the onset of clinical symptoms. c Facial image of a patient with acute TEN (number 10 patient in Table 1). Facial peeling and lip erosion. The image was taken on the eleventh day after the onset of clinical symptoms. d Arm image of a patient with acute SJS (number 8 patient in Table 1). Diffuse erythema, partial epidermolysis, flaccid vesicles, and bullae (positive Nissl's sign) on the arm. The image was taken on the tenth day after the onset of clinical symptoms. e Leg image of a patient with acute TEN (number 9 patient in Table 1). Skin sloughing on both legs. The image was taken on the fifth day after the onset of clinical symptoms. f Back image of a patient with acute TEN (number 10 patient in Table 1). Extensive peeling of the skin on the back. The image was taken on the eleventh day after the onset of clinical symptoms