Table 1 Basic information on acute SJS/TEN patients
Number | Diagnosis | Age (year) | Gender | Duration from the onset of disease (day) | Body temperature at admission (°C) | Causative medications | Other damaged skin and mucosal sites | Systemic therapy | History of systemic diseases | History of eye diseases | Disease outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | SJS | 63 | F | 8 | 37.0 | Carbamazepine | Trunk, limbs, palms, toes, back, face, oral mucosa, lips, and perineum | MePr and γ-globulin (I.V) | Hypertension and coronary heart disease | N | IR |
2 | SJS | 50 | F | 4 | 39.2 | Carbamazepine | Trunk, limbs, face, neck, oral mucosa, and perineum | MePr and γ-globulin (I.V) | Gastric ulcer and fatty liver | N | IR |
3 | SJS | 65 | M | 13 | 37.1 | Carbamazepine | Diffuse erythema present all over the body | MePr and γ-globulin (I.V) | Drug-induced liver injury and lung infection | Pterygium (OU) | IR |
4 | SJS | 41 | M | 9 | 38.2 | Carbamazepine | Trunk, limbs, face | MePr and γ-globulin (I.V) | N | N | IR |
5 | SJS | 55 | M | 8 | 37.1 | Traditional Chinese medicine, amoxicillin, and ibuprofen | Trunk, limbs, neck | MePr and γ-globulin (I.V) | Type 2 diabetes, diabetic nephropathy, and diabetic peripheral neuropathy | Diabetic retinopathy (OU) | Death |
6 | SJS | 61 | M | 6 | 37.0 | Eperisone hydrochloride | Trunk, limbs, lips, and face | MePr (I.V) | N | N | IR |
7 | SJS | 59 | F | 4 | 39.0 | Allopurinol | Trunk, limbs, face, neck, oral mucosa, sole, and perineum | MePr and γ-globulin (I.V) | Type 2 diabetes, rheumatoid arthritis, and hyperuricemia | N | IR |
8 | SJS | 50 | F | 10 | 37.1 | Unknow | Trunk, limbs, oral mucosa, lips, and perineum | MePr and γ-globulin (I.V) | Type 2 diabetes, diabetic peripheral neuropathy, diabetic ketoacidosis, lung adenocarcinoma, and fatty liver | N | IR |
9 | TEN | 67 | F | 5 | 38.5 | Unknow | Scalp, back, limbs, face | MePr and γ-globulin (I.V) | Cerebral infarction and psoriasis | Acute retinal necrosis (OU), retinal artery occlusion (OU), and retinal vasculitis (OU) | IR |
10 | TEN | 18 | F | 11 | 37.1 | Unknow | Diffuse erythema and exfoliation are present all over the body | MePr and γ-globulin (I.V) | N | N | IR |