Table 2 The Stability Analysis of Mutations by Different Web Servers
Mutation | I-Mutant 2.0 | mCSM | SDM | DUET | ENCoM | |
|---|---|---|---|---|---|---|
PAX6-V53M | ΔΔG(kcal/mol) | -0.94 | -1.083 | -0.630 | -1.058 | 0.224 |
Prediction | Destabilizing | Destabilizing | Destabilizing | Destabilizing | Destabilizing |
Mutation | I-Mutant 2.0 | mCSM | SDM | DUET | ENCoM | |
|---|---|---|---|---|---|---|
PAX6-V53M | ΔΔG(kcal/mol) | -0.94 | -1.083 | -0.630 | -1.058 | 0.224 |
Prediction | Destabilizing | Destabilizing | Destabilizing | Destabilizing | Destabilizing |