Table 4 Stratified analyses of dry eye disease for subjects with and without inflammatory bowel disease

All patients

3421

8.18

2295

5.42

1.51

1.43 (1.35 – 1.51)

< .0001

Age group, years

 0–19

259

1.67

186

1.20

1.40

1.36 (1.12 – 1.64)

0.0015

 20–39

813

6.97

524

4.44

1.57

1.49 (1.33 – 1.67)

< .0001

 40–59

1419

1.17

926

0.74

1.57

1.46 (1.34 – 1.58)

< .0001

 ≥ 60

930

1.72

659

1.19

1.45

1.32 (1.19 – 1.46)

< .0001

Sex

 Male

1034

5.02

679

3.27

1.54

1.43 (1.30 – 1.58)

< .0001

 Female

2387

11.26

1616

7.48

1.51

1.43 (1.34 – 1.52)

< .0001

Charlson comorbidity index

 0

2881

7.55

2001

5.10

1.48

1.42 (1.34 – 1.51)

< .0001

 1

431

15.40

215

9.17

1.68

1.51 (1.28 – 1.78)

< .0001

 2

90

13.25

70

11.01

1.20

1.09 (0.78 – 1.50)

0.6223

 ≥ 3

19

13.13

9

5.16

2.54

2.35 (0.99 – 5.56)

0.0519

Use of systemic corticosteroids

 Yes

756

10.21

388

7.02

1.45

1.31 (1.16 – 1.49)

< .0001

 No

2665

7.75

1907

5.18

1.50

1.45 (1.37 – 1.54)

< .0001