Table 3 Logistic regression model of the probability of treatment discontinuation

Unadjusted model

 CsA (ref OTX-101)

1.41

(1.24 to 1.61)

< 0.001^†

 LFT (ref OTX-101)

1.01

(0.89 to 1.14)

0.917

Adjusted model

 CsA (ref OTX-101)

1.35

(1.16 to 1.57)

< 0.001^†

  Age > 64 (ref ≤ 64), years

1.27

(1.07 to 1.51)

0.007^†

  Quan-CCI

0.98

(0.94 to 1.02)

0.343

  Eye-related comorbidities (ref no)

0.90

(0.76 to 1.08)

0.262

  Insurance (ref commercial)

   Employer

0.87

(0.66 to 1.15)

0.336

   Medicaid

0.62

(0.47 to 0.82)

0.001^†

   Medicare

0.94

(0.78 to 1.12)

0.478

 LFT (ref OTX-101)

0.97

(0.84 to 1.12)

0.718

  Age > 64 (ref ≤ 64), years

1.15

(0.97 to 1.37)

0.118

  Quan-CCI

0.99

(0.95 to 1.04)

0.788

  Eye-related comorbidities (ref no)

0.85

(0.72 to 1.01)

0.067

  Insurance (ref commercial)

   Employer

0.88

(0.69 to 1.10)

0.259

   Medicaid

0.79

(0.62 to 1.01)

0.060

   Medicare

0.79

(0.66 to 0.96)

0.015^†