Fig. 2

OCT images showed retinal nerve fiber layer (RNFL) thickness in eyes of patients with ICAS and without ICAS. A, B. Images of the thickness map, deviation map and quadrant values showed the superior quadrant of RNFL thinning in the ipsilateral eye of a representative case with ICAS compared with a case without ICAS. C. Comparisons of the average and four quadrants RNFL thickness between patients with and without ICAS in the ipsilateral eyes and contralateral eyes. *, p < 0.05; ns, no statistical difference. ICAS, intracranial atherosclerotic stenosis; S, superior; N, nasal; T, temporal; I, inferior; Avg, average. D. Receiver operator curves (ROC) showed the performance of retinal nerve fiber layer (RNFL) thickness in identifying intracranial atherosclerotic stenosis. The iRNFL(S), iRNFL(I) and iAvg RNFL represent the average and the superior, inferior quadrants of retinal nerve fiber layer thickness in the ipsilateral eyes, respectively. The cRNFL(S) represents the superior quadrants of retinal nerve fiber layer thickness in the contralateral eyes