Table 1 Baseline characteristics

Baseline

Age, median, IQR, years

58(43-65.3)

58 (47–66)

58(40–65)

0.611

Gender

Male, n (%)

81(79.4)

49(83.1)

32(74.4)

0.287

Female, n (%)

21(20.6)

10(16.9)

11(25.6)

Body mass index, median, IQR, kg/m2

26(23.4–28.1)

26(23.4–28.3)

25.6(23.4–27.7)

0.932

Hypertension, n (%)

69(67.6)

42(71.2)

27(62.8)

0.371

Diabetes mellitus, n (%)

28(27.5)

20(33.9)

8(18.6)

0.087

Hyperlipidemia, n (%)

41(40.2)

26(44.1)

15(34.9)

0.350

Atrial fibrillation, n (%)

3(2.9)

2(3.4)

1(2.3)

0.753

Myocardial infarction, n (%)

5(4.9)

1(1.7)

4(9.3)

0.079

Coronary artery disease, n (%)

20(19.6)

10(16.9)

10(23.3)

0.428

Alcohol use, n (%)

48(47.1)

30(50.8)

18(41.9)

0.369

Smoking, n (%)

57(55.9)

35(59.3)

22(51.2)

0.412

Family history of stroke, n (%)

25(24.5)

16(27.1)

9(20.9)

0.473

Systolic blood pressure, median (IQR)

138(125.8-153.3)

140(130–155)

134(120–153)

0.075

Diastolic blood pressure, median (IQR)

85.5(78–95)

87(79–95)

82(76–94)

0.360

Glycated hemoglobin, median (IQR)

5.8(5.3–6.3)

5.9(5.5–6.5)

5.6(5.3–6.2)

0.070

Glucose, median (IQR)

4.9(4.4–5.7)

5.1(4.4–6.4)

4.9(4.4–5.2)

0.111

Triglyceride, median (IQR)

1.3(0.9–1.6)

1.2(0.9–1.6)

1.3(0.9–1.9)

0.454

Total cholesterol, median (IQR)

3.8(3.1–4.5)

3.6(3.1–4.2)

4.1(3.2–4.7)

0.128

High-density lipoprotein, median (IQR)

1.0(0.8–1.1)

1.0(0.8–1.1)

1.0(0.8–1.1)

0.812

Low-density lipoprotein, median (IQR)

2.2(1.6–2.8)

2.1(1.6–2.5)

2.3(1.6-3.0)

0.255

Uric acid, mean (SD)

327.2 (76.8)

316.9(79.3)

341.4(71.6)

0.234

Homocysteine, median (IQR)

14.2(11.5–17.4)

14.4(12.2–17.4)

13.1(11-17.1)

0.166

Ischemic stroke, n (%)

93(91.2)

54(91.5)

39(90.7)

0.884

Large-artery atherosclersis

63(67.7)

45(83.3)

18(46.2)

< 0.001

Small-artery occlusion

11(11.8)

3(5.6)

8(20.5)

0.060

Cardioembolism

1(1.1)

0

1(1.1)

0.419

Other determined etiology

4(4.3)

1(1.9)

3(7.7)

0.306

other undetermined etiology

14(15.1)

5(9.3)

9(23.1)

0.066

TIA, n (%)

16(15.7)

8(13.6)

8(18.6)

0.489

Complications of TIA and ischemic stroke

7(6.9)

3(5.1)

4(9.3)

0.663

Complications of ischemic and hemorrhagic stroke, n (%)

2(2.0)

2(3.4)

0

0.223

Treatment

Antiplatelet drug, n (%)

95(93.1)

55(93.2)

40(93)

0.969

lipid-lowering drug, n (%)

92(90.2)

53(89.8)

39(90.7)

0.884

Endovascular treatment, n (%)

4(3.9)

3(5.1)

1(2.3)

0.636