Table 3 Clinical characteristics of BD in children compared to BD in adult patients
Pediatric Behçet’s disease | Adult Behçet’s disease | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Shahram et al., 2018 [5] | Gallizzi et al., 2017 [12] | Hu et al., 2019 [13] | Nanthapisal et al., 2016 [11] | Koné-Paut et al., 2016 [7] | Gheita et al., 2019 [14] | Gheita et al., 2019 [14] | Alpsoy et al., 2007 [16] | Davatchi et al., 2014 [9] | |||
Study country | Iran | Italy | Taiwan | UK | International Multicentric | Egypt | China | Egypt | Turkey | International multicentric | China |
N patients | 204 | 110 | 55 | 46 | 156 | 91 | 69 | 1435 | 661 | 1278 | 860 |
Age of onset symptoms (mean years ± standard deviation) | 10.5 ± 3.4 | 8.3 ± 4.1 | 11.0 (0.1–16.0) | 4,9 (0.1 – 15.7) | 7.4 ± 4.2 | 15.7 ± 2.1 | NA | 30.3 ± 8.1 | NA | NA | 36 (28 – 47)b |
Family history of BD (% of patient) | 10 | 12 | NA | 17 | 24 | NA | 22c | NA | 12 | 11 | NA |
ICBD criteria sensitivity (%) | 97 | 71 | 91 | 80 | NA | NA | 86 | NA | NA | NA | 86 |
PEDBD criteria sensitivity (%) | 69 | 46 | 36 | NA | NA | NA | 56 | NA | NA | NA | NA |
Diagnostic delay (mean years ± standard deviation) | 3.2 ± 2.6 | 2.9 ± 3.6 | NA | 3.7 (0.3—13.5) | 6.0 ± 3.5 | NA | NA | NA | 5.3 ± 6.3 | NA | NA |
M/F rate (%) | 50/50 | 56/44 | 41/59 | 48/52 | 50/50 | 69/31 | 55/45 | 72/28 | 53/47 | 57/43 | 54/46 |
Ocular involvement (%) | 66 | 44 | 27 | 9 | 45 | 76 | 9 | 75 | 29 | 55 | 18 |
Anterior uveitis (%) | 52 | 26 | NA | 4 | 30 | NA | 1 | NA | NA | 40 | 2 |
Posterior uveitis (%) | 58 | 13 | NA | 0 | 28 | NA | NA | NA | NA | 38 | NA |
Retinal vasculitis (%) | 40 | 9 | NA | 0 | 17 | NA | NA | NA | NA | 23 | NA |