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Table 3 Postoperative parameters 1 day, 1 week, and 1 month after FS-LASIK surgery

From: Moisture chamber goggles for the treatment of postoperative dry eye in patients receiving SMILE and FS-LASIK surgery

 

Control

MCG

PreOp

Po 1 Day

Po 1 Week

Po 1 Month

P1

P2

P3

PreOp

Po 1 Day

Po 1 Week

Po 1 Month

P1

P2

P3

UCVAa

-0.003 ± 0.048

0.074 ± 0.129

-0.022 ± 0.074

-0.041 ± 0.069

0.001**

0.179

0.004**

-0.012 ± 0.043

0.052 ± 0.174

-0.013 ± 0.053

-0.013 ± 0.053

0.030*

0.923

0.268

MRSE(D)

-8.10 ± 1.81

0.32 ± 0.76

-0.07 ± 0.65

-0.12 ± 0.77

 < 0.001***

 < 0.001***

 < 0.001***

-7.31 ± 1.52

0.50 ± 0.90

0.11 ± 0.65

0.02 ± 0.73

 < 0.001***

 < 0.001***

 < 0.001***

NIBUT(s)

10.17 ± 6.96

6.20 ± 5.29

6.91 ± 6.72

6.81 ± 4.95

0.008**

0.037*

0.033*

8.78 ± 6.40

7.27 ± 7.03

8.25 ± 6.63

9.04 ± 6.40

0.331

0.749

0.857

TMH(mm)

0.21 ± 0.06

0.20 ± 0.06

0.20 ± 0.04

0.22 ± 0.07

0.383

0.333

0.557

0.22 ± 0.06

0.26 ± 0.09

0.22 ± 0.06

0.22 ± 0.05

0.024*

0.887

0.628

Congestion

1.234 ± 0.159

1.164 ± 0.223

1.255 ± 0.206

1.125 ± 0.116

0.144

0.562

0.001**

1.158 ± 0.184

1.217 ± 0.365

1.055 ± 0.146

1.198 ± 0.237

0.289

 < 0.001***

0.221

AvgICU

76.35 ± 24.82

81.71 ± 23.10

72.94 ± 26.87

80.76 ± 20.74

0.381

0.597

0.360

73.61 ± 23.24

77.33 ± 23.98

59.44 ± 18.23

69.94 ± 25.80

0.456

0.004**

0.442

DevICU

18.52 ± 16.97

15.31 ± 13.86

21.53 ± 18.66

24.72 ± 18.79

0.356

0.441

0.161

20.49 ± 14.14

11.89 ± 12.28

20.14 ± 11.65

17.86 ± 15.14

0.005**

0.894

0.438

Total HOA

0.728 ± 0.676

0.414 ± 0.285

0.355 ± 0.266

0.320 ± 0.235

0.025*

0.002**

0.001**

0.608 ± 0.409

0.282 ± 0.167

0.221 ± 0.132

0.280 ± 0.177

 < 0.001***

 < 0.001***

 < 0.001***

Coma

0.317 ± 0.350

0.266 ± 0.232

0.266 ± 0.233

0.260 ± 0.207

0.538

0.442

0.349

0.303 ± 0.277

0.138 ± 0.085

0.133 ± 0.100

0.193 ± 0.160

0.002**

0.002**

0.058

Spherical

0.138 ± 0.240

-0.010 ± 0.137

0.068 ± 0.170

0.064 ± 0.141

0.002**

0.091

0.113

0.125 ± 0.165

-0.006 ± 0.097

0.021 ± 0.075

0.037 ± 0.094

 < 0.001***

0.001**

0.005**

SA

0.155 ± 0.154

0.087 ± 0.071

0.061 ± 0.051

0.031 ± 0.027

0.030*

 < 0.001***

 < 0.001***

0.128 ± 0.118

0.077 ± 0.058

0.047 ± 0.046

0.066 ± 0.050

0.031

0.001**

0.004**

Trefoil

0.403 ± 0.414

0.163 ± 0.152

0.100 ± 0.064

0.092 ± 0.055

0.002**

 < 0.001***

 < 0.001***

0.296 ± 0.211

0.121 ± 0.103

0.118 ± 0.135

0.113 ± 0.077

 < 0.001***

 < 0.001***

 < 0.001***

OSDI

17.7 ± 6.3

  

31.8 ± 12.0

  

0.020*

18.5 ± 10.7

  

14.7 ± 12.3

  

0.200

  1. P1, PreOp vs. Po 1 day; P2, PreOp vs. Po 1 week; P3, PreOp vs. Po 1 month
  2. MCG moisture chamber goggles, PreOp preoperative, Po postoperative, UCVA uncorrected visual acuity, MRSE manifest refractive spherical equivalent, TMH tear meniscus height, NIBUT non-invasive tear film break-up time, AvgICU average lipid layer thickness in interferometric color units, DevICU deviation of lipid layer thickness in interferometric color units, HOA higher-order aberrations, SA secondary astigmatism, OSDI ocular surface disease index
  3. *p < 0.05, **p < 0.01, ***p < 0.001, paired student’s t-test
  4. aBest-corrected visual acuity (BCVA) for preoperative examination