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Table 4 Subgroups analysis – depending on time of diagnosis of additional malignancies - before or after uveal melanoma (UM)

From: Additional primary malignancies in a Polish cohort of uveal melanoma patients: a review of 644 patients with long-term follow-up

 

Additional malignancies

p-value

Total

before UM

after UM

N = 121

 N = 48

 N = 73

Gender

Women

54 (45%)

24 / 50%

30 / 41%

0,3351*

Men

67 (55%)

24 / 50%

43 / 59%

Age (years)

Mean (± SD)

61

68,98 ± 9,12

64,22 ± 11,02

0,0454**

Tumours largest basal diameter (mm)

Mean (± SD)

12,25

12,63 ± 3,21

12,01 ± 2,41

0,3962**

Tumours height (mm)

Mean (± SD)

7,68

7,65 ± 2,96

7,7 ± 2,14

0,9647**

Histological type

Epithelial cell

14 /18%

5 / 17%

9 / 20%

0,00697*

Spindle cell

37 / 49%

9 / 30%

28 / 60%

Mixed cell

25 / 33%

16 / 53%

9 / 20%

TNM (8th ed) ( No. of patients / % of patients)

T1

18 / 15%

9 / 18,75%

9 / 12,3%

0,09038*

T2

41 / 34%

10 / 20,8%

31 / 42,5%

T3

45 / 37%

20 / 41,7%

25 / 34,2%

T4

17 / 14%

9 / 18,75%

8 / 11%

Stage (8th ed) ( No. of patients / % of patients)

I

13 / 11%

5 / 10,4%

8 / 10,9%

0,296*

IIA

42 / 35%

12 / 25%

30 / 41,1%

IIB

36 / 30%

16 / 33,3%

20 / 27,3%

IIIA

25 / 21%

11 / 22,9%

14 / 19,2%

IIIB

5 / 4%

4 / 8,33%

1 / 1,3%

IIIC

-

0

0

  1. *-Pearson’s chi-squared test, **Student’s t test