Skip to main content

Table 1 Study characteristics

From: Prevalence of dry eye and Meibomian gland dysfunction in Central and South America: a systematic review and meta-analysis

Design details

Characteristics of study population

Population category

Author, publication

year

Etiology

Country

Source population

Geographical locations

Data source (national,

regional, local)

Sampling scheme;

(response rate)

Female (%)

Age (years)

Race / ethnicity (%)

General population-based

Castro, 2018 [33]

DED

Brazil

Brazilian adults aged ≥ 18 years selected from general urban population, from any labor activities, workplace environment, and socioeconomic status

Brazil—North, Northeast, Central-west, Southeast, South geopolitcal regions

Population-based epidemiological study (national)

Sampling scheme—cluster sampling by geopolitical region, consecutive enrollment;

(77.7%)

65.5

Mean: 40.5

SD: 17.1

n.r

Graue-Hernandez, 2018 [41]

DED

Mexico

People aged ≥ 50 years in 39 municipalities

Tlaxcala, Mexico

Population-based epidemiological study (regional)

Sampling scheme—cluster sampling;

(58.5%)

59.6

Mean: 64.7

SD: 10.6

n.r

Working populations

Castellanos-Gonzalez, 2016 [28]

DED / MGD

Mexico

Surgical residents (physicians) of the surgical branches of the Specialty Hospital, Western National Medical Center

Guadalajara, Jalisco, Mexico

Single institution clinic or hospital-based study (local)

Sampling scheme—unspecified;

(n.r.)

27

Mean: 27.8

SD: 2.1

n.r

Sanchez-Valerio, 2020 [30]

CVS

Mexico

Office workers at the Autonomous University of Puebla

Puebla, Mexico

Population-based epidemiological study (local)

Sampling scheme—unspecified;

(n.r.)

54.6

Mean: 32.1

SD: 7.8

Range: 18 – 45

n.r

Hernandez-Llamas, 2020 [29]

DED

Mexico

Office workers at Universidad de Monterrey (UDEM) rectory office and construction workers at a new UDEM campus module

Monterrey, Mexico

Single institution clinic or hospital-based study (local)

Sampling scheme-random sampling;

(n.r.)

Construction workers

1.3

Office workers

70.3

Construction workers

Mean: 35.12

SD: 10.63

Office workers

Mean: 33.03

SD: 9.77

n.r

Student populations

Garza-Leon, 2016 [39]

DED

Mexico

All undergraduate and graduate students officially registered at University of Monterrey for the academic year 2014–2015

Monterrey, Mexico

Single institution clinic or hospital-based study (local)

Other—voluntary response sampling;

(95.7%)

59.8

Mean: 21.38

SD: 1.79

n.r

Cartes, 2021 [37]

CVS, DED

Chile

University students from different universities all over Chile who moved their classes online due to the COVID-19 pandemic

Nationwide, Chile

Population-based epidemiological study (national)

Sampling scheme—unspecified;

(27.1%)

65

Mean: 21.1

SD: 2.7

n.r

Garza-Leon, 2021 [40]

DED

Mexico

High school students from Medical Technical High School at Nuevo León Autonomous University

Monterrey, Mexico

Single institution clinic or hospital-based study (local)

Sampling scheme—non-probabalistic random sampling;

(n.r.)

55.7

Mean: 16

SD: 0.96

n.r

Hospital- and clinic-based populations

Skare, 2012 [32]

DED

Brazil

Pregnant patients in prenatal care at the Obstetrics Service and non-pregnant patients who had a gynecological appointment at the same hospital

Curitiba, Brazil

Single institution clinic or hospital-based study (local)

Sampling scheme—unspecified;

(n.r.)

100

Pregnant

Mean: 28.3

SD: 8.3;

Non-pregnant

Mean: 27.5

SD: 8.5

n.r

Martinez JD, 2016 [36]

DED/MGD

Mexico

All new patients age 16 to 85 who presented to the tertiary care outpatient clinic of a referral ophthalmology center (Asociación para Evitar la Ceguera)

Mexico City, Mexico

Single institution clinic or hospital-based study (local)

Sampling scheme -consecutive enrollment; (96.6%)

55

Mean: 45

SD: 16

n.r

Garza-Leon, 2017 [35]

DED

Mexico

Patients who attended for the first time a public or private ophthalmology high specialty center with doctors who are members of the Mexican Group of Research in Visual Sciences

19 states across Mexico

Multi-institution clinic or hospital-based study (national)

Sampling scheme -consecutive enrollment;

(n.r.)

59.4

Mean: 50.0

SD: 17.68

n.r

da Cruz, 2018 [34]

DED

Brazil

Dermatology and ophthalmology clinics of Universidade do Estado do Pará

Belém, Pará, Brazil

Single institution clinic or hospital-based study (local)

Sampling scheme—unspecified;

(n.r.)

48.8

Mean: 47.9

SD: 14.6

n.r

Surmacz, 2021 [31]

DED

Brazil

Adults who visited dermatology clinics for cosmetic reasons and treatment of superficial mycosis during the period of one year in a single Dermatological tertiary center

Curitiba, Brazil

Single institution clinic or hospital-based study (local)

Sampling scheme—convenience sampling;

(n.r.)

67.5

Median: 42

IQR: 28 – 55

Eurodescendant: 74.1;

Afrodescendant: 25.9;

Asiatic: 1.5

De Freitas, 2021 [38]

DED

Brazil

Brazilian patients seen at a single university hospital with diabetes mellitus and controls without diabetes. DM patients were recruited from a single Endocrinology outpatient clinic of a university Faculdade Evangélica Mackenzie de Curitiba, PR, Brazil hospital and controls from Dermatology Clinic seeking consultation for cosmetic reasons

Curitiba, Brazil

Single institution clinic or hospital-based study (local)

Sampling scheme—convenience sampling;

(n.r.)

Diabetes patients

57.5

Controls

55

Diabetes patients

Median 59

IQR: 47.2 – 67.0

Controls

Median 57

IQR 46.2 – 67.0

n.r

  1. CVS Computer vision syndrome, DED Dry eye disease, IQR Interquartile range, n/a Not applicable, n.r. Not reported, SD Standard deviation