Table 2 Demographics, clinical findings and outcome for patients with AMN
From: The characteristics of acute macular neuroretinopathy following COVID-19 infection
Number | Age | Sex | Laterality and quality of symptoms | Time to onset of visual symptoms after COVID RT-PCR positive | BCVA at present | Clinical Findings | BCVA at last follow-up | Outcome | Follow-up days | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NIR | SD-OCT | OCTA | ICGA | FFA | FAF | |||||||||
1 | 34 | Male | Paracentral scotoma in LE. | 2 days | R:20/20 L:20/40 | Sharply demarcated dark lesions. | Disruption of the underlying ellipsoid zones. | Decreased vascular flow signal in the deep capillary plexus. | / | / | Normal. | R:20/20 L:20/20 | Scotoma still present; ellipsoid zones were partially reversed. | 8 weeks |
2 | 42 | Male | Blurred vision in both eyes. | 3 days | R:CF L:20/100 | Lesions were not obvious. | Disruption of the underlying ellipsoid zones and outer retinal hyper-reflectivity. | Decreased vascular flow signal in the deep capillary plexus. | Normal. | Normal. | Normal. | R:20/20 L:20/20 | Visual acuity improved but scotoma still present; disruption of the underlying ellipsoid and interdigitation zones partially reversed. | 12 weeks |
3 | 37 | Male | Scotomas in central visual field in LE. | 10 days | R:20/20 L:20/25 | Dark grey lesion. | Disruption of the underlying ellipsoid and interdigitation zones. | / | Scattered small patches of low fluorescence can be seen in the late stage. | Normal. | Normal. | R:20/20 L:20/20 | Visual acuity improved but scotoma still present; ellipsoid and interdigitation zones were partially reversed. | 12 weeks |
4 | 39 | Female | Blurred vision and paracentral scotoma in both eyes. | 1 days | R:20/20 L:20/32 | Dark grey lesion. | Disruption of the underlying ellipsoid and interdigitation zones. | Decreased vascular flow signal in the deep capillary plexus. | / | / | Normal. | R:20/20 L:20/20 | Visual acuity improved but scotoma still present; disruption of the underlying ellipsoid and interdigitation zones not improved. | 16 weeks |
5 | 32 | Female | Blurred vision and paracentral scotoma in both eyes. | 2 days | R:20/25 L:20/25 | Sharply demarcated dark lesions. | Disruption of the underlying ellipsoid and interdigitation zones. | Decreased vascular flow signal in the deep capillary plexus. | Normal. | Normal. | Normal. | R:20/25 L:20/20 | Visual acuity improved but scotoma still present; disruption of the underlying ellipsoid and interdigitation zones partially reversed. | 8 weeks |
6 | 34 | Female | Blurred vision in both eyes. | 3 days | R:20/25 L:20/20 | Lesions were not obvious. | Disruption of the underlying ellipsoid and interdigitation zones. | Decreased vascular flow signal in the deep capillary plexus. | / | / | Normal. | R:20/20 L:20/20 | Visual acuity improved; disruption of the underlying ellipsoid and interdigitation zones not improved. | 12 weeks |
7 | 21 | Female | Decreased vision in both eyes. | 1 days | R:20/20 L:20/400 | Round, dark lesions in the fovea. | Disruption of ellipsoid zone and hyper-reflectivity of the outer nuclear layer. | Decreased vascular flow signal in the deep capillary plexus. | Normal. | Normal. | Normal. | R:20/20 L:20/20 | Visual acuity improved but scotoma still present; disruption of the underlying ellipsoid not improved. | 15 weeks |
8 | 16 | Male | Decreased vision in both eyes. | 2 days | R:20/25 L:20/800 | Grayish lesions in the fovea. | Disruption of ellipsoid zone and hyper-reflectivity of the outer nuclear layer. | / | Normal. | Normal. | Normal. | R:20/20 L:20/25 | Visual acuity improved but scotoma still present; disruption of the underlying ellipsoid and interdigitation zones partially reversed. | 12 weeks |
9 | 40 | Female | Blurred vision and central scotoma in both eyes. | 2 days | R:20/20 L:20/20 | Dark grey, sharply defined oval lesions. | Disruption of the underlying ellipsoid and interdigitation zones. | Decreased vascular flow signal in the deep capillary plexus. | Normal. | Normal. | Normal. | scotoma still present; disruption of the underlying ellipsoid and interdigitation zones partially reversed. | 20 weeks | |
10 | 36 | Female | Central scotoma in both eyes. | 2 days | R:20/20 L:20/20 | Well- demarcated, petalloid-shaped, dark grey macular lesions. | Disruption of ellipsoid zone and hyper-reflectivity of the outer nuclear layer. | Decreased vascular flow signal in the deep capillary plexus. | / | / | Normal. | scotoma still present; disruption of the underlying ellipsoid and interdigitation zones partially reversed. | 15 weeks | |
11 | 41 | Female | Decreased vision in both eyes. | 3 days | R:20/25 L:20/40 | Dark grey lesion. | Disruption of ellipsoid zone and hyper-reflectivity of the outer nuclear layer. | / | Scattered small patches of low fluorescence can be seen in the early and late stage. | Normal. | Normal. | Visual acuity improved; disruption of the underlying ellipsoid and interdigitation zones partially reversed; outer nuclear layer atrophy. | 8 weeks | |