Fig. 2
From: When the second comes first– rhabdomyosarcoma preceding heritable retinoblastoma– a case report
Bilateral nodular multifocal deformations of both lower extremities from alveolar RMS metastases (A) confirmed on histopathology showing nests and sheets of undifferentiated round tumor cells with rhabdoid features infiltrating the striated muscle (hematoxylin and eosin, magnification X126) (B). Immunostaining of the tumor tissue displaying RB1 loss in most of the tumor nuclei (magnification X126) (C)