Fig. 1

(A) Principal component analysis (PCA) of wBC/RSN transformed MFI data across all analytes. The x-axis represents PC1 which accounts for 44.89% of the total variation, while the y-axis represents PC2, accounting for 13.77% of the variation. The data points are colored according to their group, while the 95% concentration ellipses are shown to aid in the interpretation of the groupings. (B) Heatmap showing wBC/RSN transformed MFI levels across analytes identified as significantly different between healthy and patient groups based on raw p-value < 0.05. Columns were standardized and then both rows and columns were clustered based on complete linkage using Euclidean distance