Fig. 3
From: Identification of biomarker candidates for exfoliative glaucoma from autoimmunity profiling
(A) Bar chart showing significantly (adj. p < 0.05) enriched gene sets in a list of genes associated with differentially expressed analytes, as compared against MSigDB C2 gene sets, sorted by ratio of significant over total genes in set (k/K). Several pathways identified as enriched correspond to collagen formation, a process hypothesized to be related to the pathogenesis of XFG. (B) Bar chart showing significantly (adj. p < 0.05) enriched gene sets, as compared against MsigDB C3 gene sets. Targets of miRNAs 3167 and 876-5P are the highest enrichment among the regulatory set, and contain many of the same genes implicated in the C2 gene sets