Study on the correlation between iris blood flow, iris thickness and pupil diameter in the resting state and after pharmacological mydriasis in patients with diabetes mellitus

Table 3 The changes of iris parameters after drug-induced mydriasis among type 2 diabetes mellitus adults and healthy adults

	Parameters	Healthy Adults N = 50	T2DM Adults N = 52	P value
Baseline
	Pupil Diameter	4.77 ± 0.80	4.42 ± 0.84	0.050
	Whole VAD	0.21 ± 0.05	0.21 ± 0.06	0.550
	Whole VSD	0.15 ± 0.04	0.16 ± 0.04	0.095
	Outer 2/3VAD	0.20 ± 0.07	0.20 ± 0.07	0.786
	Outer 2/3VSD	0.15 ± 0.05	0.15 ± 0.05	0.854
	Pupillary Margin VAD	0.27 ± 0.06	0.29 ± 0.09	0.308
	Pupillary Margin VSD	0.18 ± 0.04	0.21 ± 0.05	0.008
	Iris Thickness at SMR	0.48 ± 0.11	0.45 ± 0.09	0.173
	Iris Thickness at DMR	0.50 ± 0.08	0.44 ± 0.11	0.014
	Iris volume	36.58 ± 4.28	35.22 ± 4.87	0.175
After Mydriasis
	Pupil Diameter	7.58 ± 0.68	7.19 ± 0.68	0.011
	Whole VAD	0.30 ± 0.08	0.28 ± 0.10	0.337
	Whole VSD	0.21 ± 0.05	0.22 ± 0.06	0.829
	Outer 2/3VAD	0.29 ± 0.06	0.28 ± 0.07	0.655
	Outer 2/3VSD	0.21 ± 0.06	0.22 ± 0.06	0.763
	Pupillary Margin VAD	0.32 ± 0.08	0.30 ± 0.11	0.301
	Pupillary Margin VSD	0.22 ± 0.05	0.22 ± 0.06	0.736
	Iris volume	29.38 ± 3.97	29.44 ± 4.75	0.949

T2DM = type 2 diabetes mellitus; VAD = vessel area density; VSD = vessel skeleton density; SMR = sphincter muscle region; DMR = dilator muscle region

ISSN: 1471-2415