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Table 3 CNV-PED complex, RNFL, and Amp-P1 before and after treatment (N = 40)

From: Efficacy and safety of intravitreal injections of conbercept for the treatment of idiopathic choroidal neovascularization

Indices (mean ± SD)

Preoperative

1 month

3 months

6 months

12 months

CNV-PED complex (μm)

148.0 ± 13.15

119.7 ± 10.18* ^

95.68 ± 9.39* ^

89.75 ± 13.44* ^

84.33 ± 10.75*

*p value

< 0.0001

< 0.0001

< 0.0001

< 0.0001

^p value

< 0.0001

< 0.0001

0.0497

RNFL (μm)

105.0 ± 8.14

104.4 ± 7.89# ^

104.3 ± 6.98# ^

104.3 ± 7.63# ^

104.8 ± 7.90#

#p value

0.7977

0.0904

0.938

0.4489

^p value

0.7902

0.7650

0.7742

Amp-P1(nv/deg2)

49.08 ± 9.89

57.85 ± 9.65* ^

61.23 ± 9.38* ^

63.48 ± 8.96* ^

64.65 ± 6.50*

*p value

< 0.0001

< 0.0001

< 0.0001

< 0.0001

^p value

0.0017

0.0624

0.4501

  1. CNV-PED choroidal neovascularization-pigment epithelial detachment, RNFL retinal nerve fiber layer, Amp-P1 the first positive peak (P1) amplitude density. #P > 0.05,*P < 0.05 compared with the data before treatment. ^vs data at 12 months. The independent sample t-test or Mann-Whitney test was used to compare the values at 1, 3, and 6 months after treatment with the last follow-up. The paired t-test or Wilcoxon signed-rank test was used to compare the values after treatment with those before treatment