Fig. 3

Multimodal imaging of choroidal neovascularization secondary to laser injury. (A) Infrared reflectance image obtained at approximately four months after the injury illustrates progression of an epiretinal membrane with vitreomacular traction. The green arrow shows the position of the scan line used to generate the cross-sectional retinal OCT image. (B) SD-OCT cross-sectional retinal image through the macular scar demonstrates increasing retinal thickness with reactive gliosis and intraretinal and subretinal hyperreflective material. (C) Fluorescein angiography of the right eye in the early arteriovenous phase demonstrates absences of retinal vessels in the region of the macular scar with adjacent hyperfluorescence corresponding to a neovascular lesion (17 s). (D) The fluorescence from the neovascular lesion increases during the intermediate phase (2 min 10 s), with increasing leakage in the late phases (not shown). (E) Infrared reflectance image obtained six months later demonstrates resolution of the fibrovascular membrane complex. The green arrow shows the position of the scan line used to generate the cross-sectional retinal OCT image. (F) SD-OCT cross-sectional retinal image through the macula reveals a remarkable resolution of the of the epiretinal membrane with improvement in macular contour and regression of the choroidal neovascular membrane. A tuft of scar tissue is all that remains of the fibrovascular complex. Scale bar: 500 μm